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Ruth Langley

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University College London

United Kingdom

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Add-Aspirin Trial: A phase III double-blind placebo-controlled randomized trial assessing the addition of aspirin after standard primary therapy in early stage common solid tumours

Open Date: 2014-05-01

Close Date: 2026-04-30

Grant: Close

CRUK/12/033: Add-Aspirin Trial- A phase III double-blind placebo-controlled randomized trial assessing the addition of aspirin after standard primary therapy in early stage common solid tumours

Open Date: 2013-09-01

Close Date: 2025-08-31

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Collaborators (12)

Duncan Gilbert

University College London

UNITED KINGDOM

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Heike I Grabsch

Professor

University of Leeds

UNITED KINGDOM

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Hoda Abdel-Aty

Institute of Cancer Research

UNITED KINGDOM

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John Burn

UNITED KINGDOM

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Trinh Duong

University College London

UNITED KINGDOM

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Henry Woodruff

Associate Professor

University of Maastricht

NETHERLANDS

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Derek Magee

Associate Professor

University of Leeds

UNITED KINGDOM

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Eleni Frangou

University of Oxford

UNITED KINGDOM

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Louise Brown

University College London

UNITED KINGDOM

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Annabelle South

University College London

UNITED KINGDOM

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Nicholas James

Professor of Prostate and Bladder Cancer Research

Institute of Cancer Research

UNITED KINGDOM

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Jamie Stokes

University of Oxford

UNITED KINGDOM

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Ruth Langley

Research Interests

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Recent Grants

Articles (19)

Health-related quality of life with adjuvant immune checkpoint inhibition in renal cell carcinoma: A qualitative study of UK participants in the phase III RAMPART trial

Validation of tumour-negative lymph node size as a novel independent prognostic biomarker in oesophagogastric adenocarcinoma: post hoc analysis of the UK MRC OE05 and ST03 randomised trials

The density of tumour infiltrating lymphocytes in oesophago-gastric cancer varies with disease stage, geographical region and treatment: a post hoc analysis of nine phase III clinical trials

A Hybrid Transformer-Graph Model for Multi-Class Lymph Node Segmentation in Histopathology

On-treatment serum prostate-specific antigen and overall survival in prostate cancer (STAMPEDE platform protocol): a post-hoc analysis of data from five phase 3 trials.

Transdermal Estradiol Patches in Locally Advanced Prostate Cancer.

Drug re-purposing to improve outcomes in the management of prostate cancer - aims, outcome measures and design of current phase III trials.

Authors' Reply: “Healthcare Systems Data to Improve the Efficiency of Clinical Trials Within the UK: A Prospectively Planned Comparison of Healthcare Systems Data and Trial-reported Outcomes Within the Add-Aspirin Cancer Clinical Trial”

Transdermal Estradiol Patches in Prostate Cancer [The authors reply]

Healthcare Systems Data (HSD) to Improve the Efficiency of Clinical Trials Within the UK: A Prospectively Planned Comparison of HSD and Trial-Reported Outcomes Within the Add-Aspirin Cancer Clinical Trial

The role of DNA mismatch repair status in oesophagogastric cancer treated with perioperative chemotherapy: evidence from the MRC ST03 and OE05 trials

Platelet activation, aspirin, and cancer: From basic science to clinical trials

Metformin for patients with metastatic prostate cancer starting androgen deprivation therapy: a randomised phase 3 trial of the STAMPEDE platform protocol

Determining the Impact of Histology on the Incidence, Pattern, and Timing of Recurrences in Patients with Renal Cell Carcinoma: A Pooled Analysis from the SORCE and ASSURE Trials

Preferences between three options for androgen deprivation therapy: a focus group study

Intra-patient comparison of microarchitecture of tumour negative lymph nodes from oesophageal cancer patients - Results from the MRC Oe02 trial

Understanding How Aspirin Prevents Metastasis

Suspending the NHS medicines repurposing programme in England is a missed opportunity

Determining the optimal use of approved drugs in oncology.

Collaborators (12)

Duncan Gilbert

Heike I Grabsch

Hoda Abdel-Aty

John Burn

Trinh Duong

Henry Woodruff

Derek Magee

Eleni Frangou

Louise Brown

Annabelle South

Nicholas James

Jamie Stokes

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