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Ryan Roberts

Principal Investigator

Nationwide Children's Hospital

United States

Research Interests

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Articles (20)

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2025

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2025

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2025

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2023

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2023

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2023

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2023

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2023

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2023

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2022

Collaborators (14)

Matthew Dietz

Assistant Professor

University of Utah

UNITED STATES

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Joshua D. Palmer

Ohio State University

UNITED STATES

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Roshni Dasgupta

professor

UNITED STATES

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Ajay Gupta

Assistant Professor

Roswell Park Comprehensive Cancer Center

UNITED STATES

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Ruben Dries

Assistant Professor of Medicine

Boston University

UNITED STATES

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Catherine E. Cottrell

Nationwide Children's Hospital

UNITED STATES

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Alexander Davies

Assistant Professor

Oregon Health & Science University

UNITED STATES

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Carlos J Miranda

VP, Head of Preclinical

Biological E. Limited

UNITED KINGDOM

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Michael Arnold

Associate Professor

Stanford University

UNITED STATES

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Angela C. Hirbe

Washington University School of Medicine

UNITED STATES

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Lijun Cheng

Associate Professor

The Ohio State University Wexner Medical Center

UNITED STATES

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James Reinecke

Assistant professor

Nationwide Children's Hospital

UNITED STATES

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Jennifer Aldrink

Professor of Clinical Surgery and Pediatrics

Nationwide Children's Hospital

UNITED STATES

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Erin Talbert

Assistant Professor

Iowa State University

UNITED STATES

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Ryan Roberts

Research Interests

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Articles (20)

Aberrant Activation of Wound-Healing Programs within the Metastatic Niche Facilitates Lung Colonization by Osteosarcoma Cells

Optimizing Ewing Sarcoma and Osteosarcoma Biopsy Acquisition: A Children’s Oncology Group Bone Tumor Committee Consensus Statement

Local Control and Toxicity Outcomes After Stereotactic Body Radiation Therapy for Metastatic Osteosarcoma in Pediatric Patients

MyoD is essential in rhabdomyosarcoma by promoting survival through differentiation and CYLD.

ReNeu: A Pivotal, Phase IIb Trial of Mirdametinib in Adults and Children With Symptomatic Neurofibromatosis Type 1-Associated Plexiform Neurofibroma

Disease Control and Toxicity Outcomes after Stereotactic Ablative Radiation Therapy for Recurrent and/or Metastatic Cancers in Young-Adult and Pediatric Patients

Employing splice-switching oligonucleotides and AAVrh74.U7 snRNA to target insulin receptor splicing and cancer hallmarks in osteosarcoma

In vitro medulloblastoma leptomeningeal metastasis models reveal adhesion signaling as a therapeutic vulnerability

Inflammatory paracrine loops established between metastasis-initiating cells and alveolar epithelium drive interactions between tumor cell subtypes that are essential for osteosarcoma lung colonization

Progress in sarcomas: Highlights from the 2023 annual meeting of the Connective Tissue Oncology Society

Synergistic mechanisms against pediatric bone sarcoma models: Trabectedin enhances oncolytic virotherapy intratumoral spread and antitumor immune activation

Trabectedin promotes oncolytic virus antitumor efficacy, viral gene expression, and immune effector function in models of bone sarcoma

Treatment with novel topoisomerase inhibitors in Ewing sarcoma models reveals heterogeneity of tumor response

Host-derived growth factors drive ERK phosphorylation and MCL1 expression to promote osteosarcoma cell survival during metastatic lung colonization

Osteosarcoma Multi-Omics Landscape and Subtypes

Aberrant activation and perpetuation of lung wound response facilitates osteosarcoma metastasis

Molecularly Defined Subsets of Ewing Sarcoma Tumors Differ in Their Responses to IGF1R and WEE1 Inhibition

Oncolytic virus-driven immune remodeling revealed in mouse medulloblastomas at single cell resolution

Osteosarcoma tumors maintain intra-tumoral transcriptional heterogeneity during bone and lung colonization

EGFR internal tandem duplications in fusion-negative congenital and neonatal spindle cell tumors.

Collaborators (14)

Matthew Dietz

Joshua D. Palmer

Roshni Dasgupta

Ajay Gupta

Ruben Dries

Catherine E. Cottrell

Alexander Davies

Carlos J Miranda

Michael Arnold

Angela C. Hirbe

Lijun Cheng

James Reinecke

Jennifer Aldrink

Erin Talbert

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