Ryota Shizu

Shizuoka University

Japan

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Articles (16)

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2025

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2025

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2025

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2025

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2024

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2023

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2021

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2021

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2021

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2021

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2021

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2021

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2021

Collaborators (5)

Yuichiro Kanno

Assistant Professor

Shizuoka University

JAPAN

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HIsamitsu Ishihara

Nihon University School of Medicine

JAPAN

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Jun-ichi Takeshita

National Institute of Advanced Industrial Science and Technology (AIST)

JAPAN

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Kouichi Yoshinari

Professor

Shizuoka University

JAPAN

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Yukiko Kaneko

Shizuoka University

JAPAN

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Ryota Shizu

Research Interests

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Articles (16)

Utility of in vitro assay data in read-across prediction of nongenotoxic carcinogenicity of pesticides for cytotoxicity-related rat tumors

Machine Learning on Toxicogenomic Data Reveals a Strong Association Between the Induction of Drug-Metabolizing Enzymes and Centrilobular Hepatocyte Hypertrophy in Rats

Comparative study on gene expression profiles in the liver of male neonatal mice prenatally exposed to PFOA and its alternative HFPO-DA

Diacylglycerol kinase ζ is a positive insulin secretion regulator in pancreatic β-cell line MIN6

Utility of human cytochrome P450 inhibition data in the assessment of drug-induced liver injury

Pregnane X receptor inhibits the transdifferentiation of hepatic stellate cells by down-regulating periostin expression

PPARα Induces the Expression of CAR That Works as a Negative Regulator of PPARα Functions in Mouse Livers

Possible Involvement of the Upregulation of ΔNp63 Expression Mediated by HER2-Activated Aryl Hydrocarbon Receptor in Mammosphere Maintenance

Distinct Roles of the Sister Nuclear Receptors PXR and CAR in Liver Cancer Development

Chemical characterization of anemia-inducing aniline-related substances and their application to the construction of a decision tree-based anemia prediction model

Helix 12 stabilization contributes to basal transcriptional activity of PXR

Identification of average molecular weight (AMW) as a useful chemical descriptor to discriminate liver injury-inducing drugs

PXR Suppresses PPARα-Dependent HMGCS2 Gene Transcription by Inhibiting the Interaction between PPARα and PGC1α

Glucocorticoid receptor dimerization in the cytoplasm might be essential for nuclear localization

The influence of the long-term chemical activation of the nuclear receptor pregnane X receptor (PXR) on liver carcinogenesis in mice.

Association of CYP1A1 and CYP1B1 inhibition in in vitro assays with drug-induced liver injury

Collaborators (5)

Yuichiro Kanno

HIsamitsu Ishihara

Jun-ichi Takeshita

Kouichi Yoshinari

Yukiko Kaneko

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