Ryuji Kubota

Professor

Kagoshima University

Japan

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Professor Ryuji Kubota is a faculty member at Kagoshima University in Japan. His research focuses on various aspects of Human T-lymphotropic virus type 1 (HTLV-1), including its implications in neurological diseases and the characteristics of T-cell responses. Recent publications explore topics such as antiviral efficacy, T-cell receptor dynamics, and diagnostic evaluations related to HTLV-1 infections.

Articles (16)

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2025

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2025

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2024

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2023

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2023

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2023

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2022

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2022

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2021

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2020

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2020

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2020

Collaborators (4)

Yoshimi Enose-Akahata

National Institute of Neurological Disorders and Stroke

UNITED STATES

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Mineki Saito

Professor

Kawasaki Medical School

JAPAN

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Masakazu Tanaka

Associate Professor

Kagoshima University

JAPAN

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Teruto Hashiguchi

Kagoshima University

JAPAN

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Ryuji Kubota

Research Interests

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Articles (16)

High TCR Degeneracy Enhances Antiviral Efficacy of HTLV-1-Specific CTLs by Targeting Variant Viruses in HAM Patients

T-Cell Receptor/CD3 Downregulation and Impaired Signaling in HTLV-1-Infected CD4+ T Cells of HAM Patients

M-Sec promotes the accumulation of intracellular HTLV-1 Gag puncta and the incorporation of Env into viral particles.

HLA-A*24 Increases the Risk of HTLV-1-Associated Myelopathy despite Reducing HTLV-1 Proviral Load.

Geographic characteristics of HTLV-1 molecular subgroups and genetic substitutions in East Asia: Insights from complete genome sequencing of HTLV-1 strains isolated in Taiwan and Japan.

HTLV-1-associated myelopathy/tropical spastic paraplegia with sporadic late-onset nemaline myopathy: a case report.

Iliopsoas Muscle Weakness as a Key Diagnostic Marker in HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP).

Identification and tracking of HTLV-1-infected T cell clones in virus-associated neurologic disease.

Anti-ganglionic acetylcholine receptor antibodies in functional neurological symptom disorder/conversion disorder.

Performance evaluation of Espline HTLV-I/II, a newly developed rapid immunochromatographic antibody test for different diagnostic situations.

Efficacy of l-Arginine treatment in patients with HTLV-1-associated neurological disease.

High Prevalence of HTLV-1 Carriers among the Elderly Population in Kagoshima, a Highly Endemic Area in Japan

Anti-human T-cell Leukemia virus type 1 (HTLV-1) antibody assays in cerebrospinal fluid for the diagnosis of HTLV-1 associated myelopathy/tropical spastic paraparesis

Establishment of a novel diagnostic test algorithm for human T-cell leukemia virus type 1 infection with line immunoassay replacement of western blotting: a collaborative study for performance evaluation of diagnostic assays in Japan.

Human T-lymphotropic virus type 1 (HTLV-1) and cellular immune response in HTLV-1-associated myelopathy/tropical spastic paraparesis.

Inhibition of ABL1 tyrosine kinase reduces HTLV-1 proviral loads in peripheral blood mononuclear cells from patients with HTLV-1-associated myelopathy/tropical spastic paraparesis.

Collaborators (4)

Yoshimi Enose-Akahata

Mineki Saito

Masakazu Tanaka

Teruto Hashiguchi

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