S. Makhseed

Tuning the amphiphilicity of (aza)phthalocyanine hydrophobic cores by introducing multiple polyethylene glycol (PEG) moieties with controlled orientations of their (non)peripheral positions is an innovative approach to fabricating water‐soluble macrocyclic materials. Although many water‐soluble PEGylated macrocycles have been produced in this way, the ability to generate substances with PEG tails oriented outward from the macrocyclic plane in order to obtain non‐aggregated, water soluble forms remains a challenge. In this study, we resolved this issue by developing a methods for the synthesis of four new dual directional PEG containing Zn(II)/Mg(II) amphiphiles ( ZnPc−PEG , MgPc−PEG , ZnAzaPc−PEG and MgAzaPc−PEG ). In addition, the non‐aggregating behaviour, and photophysical and photochemical properties of these PEG‐complexes were elucidated.