Sakthivel Vaiyapuri

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Professor in Cardiovascular & Venom Pharmacology

University of Reading

United Kingdom

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About

Dr. Sakthivel Vaiyapuri is a Professor in Cardiovascular & Venom Pharmacology at the University of Reading, UK. His research focuses on the effects of venom from various snakes and arachnids on human physiology, particularly its implications for muscle regeneration, anticoagulation, and skeletal muscle damage. He has contributed to several studies exploring the versatility of venom-derived components and their potential applications in drug discovery.

Recent Grants

Grant: Close

Novel signalling axis to control thromboinflammation in ageing and COVID-19

Open Date: 2021-07-01

Close Date: 2022-06-01

Grant: Close

Research Policy Engagement for snakebite envenomation

Open Date: 2021-01-01

Close Date: 2021-03-01

Grant: Close

Transcriptomics analysis for snakebite-induced muscle damage

Open Date: 2021-01-01

Close Date: 2021-07-01

Grant: Close

Role of venom toxins in the attenuation of muscle stem cell function during the development of snakebite-induced permanent disabilities

Open Date: 2020-10-01

Close Date: 2021-09-01

Grant: Close

Beneficial effects of small molecules isolated from cannabis to control heart attacks and strokes

Open Date: 2020-10-01

Close Date: 2021-09-01

Articles (16)

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2025

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2023

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2023

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2023

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2023

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2023

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2023

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2023

Collaborators (5)

Stephen Mackessy

Professor of Biology

University of Northern Colorado

UNITED STATES

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Matthew Cooper

Professor

University of Queensland

AUSTRALIA

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José Rafael de Almeida

University of Reading

UNITED KINGDOM

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Olli Ritvos

Associate Professor/Senior Lecturer (full time; tenured)

University of Helsinki

FINLAND

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Tapan K. Mohanta

OMAN

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Sakthivel Vaiyapuri

Research Interests

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About

Recent Grants

Articles (16)

Soluble Activin Receptor Type IIB Improves Muscle Regeneration Following Crotalus atrox Venom-Induced Damage

Correction: Richards et al. Indian Ornamental Tarantula (<i>Poecilotheria regalis</i>) Venom Affects Myoblast Function and Causes Skeletal Muscle Damage. <i>Cells</i> 2023, <i>12</i>, 2074

The Versatility of Serine Proteases from Brazilian <i>Bothrops</i> Venom: Their Roles in Snakebites and Drug Discovery

Pulmonary Thromboembolism following Russell’s Viper Bites

Antibacterial and Antiviral Properties of Chenopodin-Derived Synthetic Peptides

In vitro anticoagulant effects of Bungarus venoms on human plasma which are effectively neutralized by the PLA2-inhibitor varespladib

Snakebite-induced reversible cerebral vasoconstriction syndrome: Report of three cases

Reply to Jalink, M.B. Comment on “Senthilkumaran et al. Bilateral Simultaneous Optic Neuritis Following Envenomations by Indian Cobra and Common Krait. Toxins 2022, 14, 805”

Purification of PaTx-II from the Venom of the Australian King Brown Snake and Characterization of Its Antimicrobial and Wound Healing Activities

Partial segmental thrombosis of the corpus cavernosum following Russell's viper bite

Indian Ornamental Tarantula (<i>Poecilotheria regalis</i>) Venom Affects Myoblast Function and Causes Skeletal Muscle Damage

Intramuscular Bleeding and Formation of Microthrombi during Skeletal Muscle Damage Caused by a Snake Venom Metalloprotease and a Cardiotoxin

Neutrophil-mediated erythrophagocytosis following Russell's viper (Daboia russelii) bite

Ashes to eye: A skilled snake handler’s experience with ophthalmic envenomation

The Effectiveness of Antibiotics in Managing Bacterial Infections on Bite Sites following Snakebite Envenomation

Deletion of Annexin A1 in Mice Upregulates the Expression of Its Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic Peptide in Platelets

Collaborators (5)

Stephen Mackessy

Matthew Cooper

José Rafael de Almeida

Olli Ritvos

Tapan K. Mohanta

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