Sam Hughes

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Senior Lecturer in Pain Neuroscience

University of Exeter

United Kingdom

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Sam Hughes is a Senior Lecturer in Pain Neuroscience at the University of Exeter, United Kingdom. His research primarily focuses on the intersection of pain modulation and immersive technologies, particularly through the use of virtual reality. Recent articles authored by Dr. Hughes explore topics such as secondary hyperalgesia, the therapeutic effects of nature for chronic pain, and the reliability of sensory testing in pain assessment.

Recent Grants

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Neurotechnology for Chronic Pain

Open Date: 2022-05-31

Close Date: 2025-05-30

Articles (13)

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2025

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2020

Collaborators (5)

Kayleigh Wyles

Associate Professor

University of Plymouth

UNITED KINGDOM

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Matthew Howard

King’s College London

UNITED KINGDOM

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Paul Strutton

Imperial College London

UNITED KINGDOM

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Patricia Schofield

Professor of Clinical Nursing

University of Plymouth

UNITED KINGDOM

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kirsty bannister

Lecturer

King’s College London

UNITED KINGDOM

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Sam Hughes

Research Interests

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About

Recent Grants

Articles (13)

Investigating the Influence of Experimentally Induced Secondary Hyperalgesia on Pain Prediction Error Encoding in Healthy Individuals: A Novel Virtual Reality Protocol

Immersion in nature through virtual reality attenuates the development and spread of mechanical secondary hyperalgesia: a role for insulo-thalamic effective connectivity

“Being away from everything”: Exploring the importance of access to nature for individuals living with chronic low back pain

Harnessing the therapeutic effects of nature for chronic Pain: A role for immersive virtual reality? A narrative review

Virtual reality-based analgesia: towards a novel framework for the biopsychosocial management of chronic pain

Responders and nonresponders to topical capsaicin display distinct temporal summation of pain profiles

Reliability of quantitative sensory testing in the assessment of somatosensory function after high-frequency stimulation–induced sensitisation of central nociceptive pathways

Responders and nonresponders to topical capsaicin display distinct temporal summation of pain profiles

One size does not fit all: towards optimising the therapeutic potential of endogenous pain modulatory systems.

Exposure to an Immersive Virtual Reality Environment can Modulate Perceptual Correlates of Endogenous Analgesia and Central Sensitization in Healthy Volunteers

Anodal transcranial direct current stimulation over the primary motor cortex attenuates capsaicin‐induced dynamic mechanical allodynia and mechanical pain sensitivity in humans

Diffusion tensor imaging of lumbar spinal nerves reveals changes in microstructural integrity following decompression surgery associated with improvements in clinical symptoms: A case report

Capsaicin-Induced Changes in Electrical Pain Perception Threshold Can Be Used to Assess the Magnitude of Secondary Hyperalgesia in Humans

Collaborators (5)

Kayleigh Wyles

Matthew Howard

Paul Strutton

Patricia Schofield

kirsty bannister

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