Sanbing Shen

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Professor of Fundamental Stem Cell Biology

National University of Ireland Galway

Ireland

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About

Sanbing Shen is a Professor of Fundamental Stem Cell Biology at the National University of Ireland Galway. His research focuses on various aspects of stem cell biology, including longevity, diabetic complications, and cardiac health, as highlighted in his recent articles on telomerase, iPSC-derived neurons, and therapeutic applications of mesenchymal stromal cells. He is particularly interested in the applications of induced pluripotent stem cells in organoid development and disease modeling.

Recent Grants

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Screening and Characterization of Chinese Medicine for Cancer Using Gene-edited Cancer Stem Cells and Human iPSCs (Lin Cheng)

Open Date: 2022-09-01

Close Date: 2026-08-01

Grant: Close

Investigate LQT heart disease mechanism and therapy using iPSCs.

Open Date: 2021-11-01

Close Date: 2023-10-01

Grant: Close

Investigate LQTS mechanism and therapy using iPSCs.

Open Date: 2021-11-01

Close Date: 2023-10-01

Grant: Close

Molecular Mechanism and Drug Exploration of Autism Using Human Induced Pluripotent Stem Cells (Wenxin Xia)

Open Date: 2021-09-01

Close Date: 2025-08-01

Grant: Close

Cardiac stem cell research

Open Date: 2021-09-01

Close Date: 2023-08-01

Articles (19)

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2024

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2023

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2021

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2021

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2021

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (4)

Timothy O’Brien

IRELAND

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Amirhossein Jalali

Lecturer in Biostatstics

University of Limerick

IRELAND

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Jing Wang

FRANCE

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Jérôme Ruel

Associate Professeur-HDR (Neuroscience)

Aix-Marseille University

FRANCE

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Sanbing Shen

Research Interests

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About

Recent Grants

Articles (19)

Telomerase reverse transcriptase gene knock‐in unleashes enhanced longevity and accelerated damage repair in mice

Polyethyleneimine facilitates the growth and electrophysiological characterization of iPSC-derived motor neurons

Defining Cardiomyocyte Repolarization Response to Pharmacotherapy in Long‐QT Syndrome Type 3

Human umbilical cord-derived mesenchymal stromal cells improve myocardial fibrosis and restore miRNA-133a expression in diabetic cardiomyopathy

Amelioration of diabetic nephropathy in mice by a single intravenous injection of human mesenchymal stromal cells at early and later disease stages is associated with restoration of autophagy

Application Prospect of Induced Pluripotent Stem Cells in Organoids and Cell Therapy

The putative protein kinase Stk36 is essential for ciliogenesis and CSF flow by associating with Ulk4

Using Ribonucleoprotein-based CRISPR/Cas9 to Edit Single Nucleotide on Human Induced Pluripotent Stem Cells to Model Type 3 Long QT Syndrome (SCN5A±)

A novel protocol to derive cervical motor neurons from induced pluripotent stem cells for amyotrophic lateral sclerosis

Generation of three induced pluripotent stem cell lines from a patient with KCNQ2 developmental and epileptic encephalopathy as a result of the pathogenic variant c.881C > T; p.Ala294Val (NUIGi059-A, NUIGi059-B, NUIGi059-C) and 3 healthy controls (NUIGi060-A, NUIGi060-B, NUIGi060-C)

NRXN1α+/- is associated with increased excitability in ASD iPSC-derived neurons

Endogenous Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Plays a Protective Effect Against Noise-Induced Hearing Loss.

Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual.

Derivation and characterization of two human induced pluripotent stem cell lines (NUIGi004-A) and (NUIGi012-A) from two patients with LQT2 disease.

Generation and characterization of three induced pluripotent stem cell lines (NUIGi047-A, NUIGi047-B, NUIGi047-C) from a 7-year-old healthy Caucasian male.

Derivation of four iPSC lines from a male ASD patient carrying a deletion in the middle coding region of NRXN1α gene (NUIGi039-A and NUIGi039-B) and a male sibling control (NUIGi040-A and NUIGi040-B).

Derivation of iPSC lines from two patients with autism spectrum disorder carrying NRXN1α deletion (NUIGi041-A, NUIG041-B; NUIGi045-A) and one sibling control (NUIGi042-A, NUIGi042-B).

Coupling of autism genes to tissue-wide expression and dysfunction of synapse, calcium signalling and transcriptional regulation.

Derivation of iPSC lines from three young healthy donors of Caucasian origin (NUIGi035-A; NUIGi036-A; NUIGi037-A).

Collaborators (4)

Timothy O’Brien

Amirhossein Jalali

Jing Wang

Jérôme Ruel

Make your next move.

Sanbing Shen

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (19)

Telomerase reverse transcriptase gene knock‐in unleashes enhanced longevity and accelerated damage repair in mice

Polyethyleneimine facilitates the growth and electrophysiological characterization of iPSC-derived motor neurons

Defining Cardiomyocyte Repolarization Response to Pharmacotherapy in Long‐QT Syndrome Type 3

Human umbilical cord-derived mesenchymal stromal cells improve myocardial fibrosis and restore miRNA-133a expression in diabetic cardiomyopathy

Amelioration of diabetic nephropathy in mice by a single intravenous injection of human mesenchymal stromal cells at early and later disease stages is associated with restoration of autophagy

Application Prospect of Induced Pluripotent Stem Cells in Organoids and Cell Therapy

The putative protein kinase Stk36 is essential for ciliogenesis and CSF flow by associating with Ulk4

Using Ribonucleoprotein-based CRISPR/Cas9 to Edit Single Nucleotide on Human Induced Pluripotent Stem Cells to Model Type 3 Long QT Syndrome (SCN5A±)

A novel protocol to derive cervical motor neurons from induced pluripotent stem cells for amyotrophic lateral sclerosis

Generation of three induced pluripotent stem cell lines from a patient with KCNQ2 developmental and epileptic encephalopathy as a result of the pathogenic variant c.881C &gt; T; p.Ala294Val (NUIGi059-A, NUIGi059-B, NUIGi059-C) and 3 healthy controls (NUIGi060-A, NUIGi060-B, NUIGi060-C)

NRXN1α+/- is associated with increased excitability in ASD iPSC-derived neurons

Endogenous Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Plays a Protective Effect Against Noise-Induced Hearing Loss.

Generation and characterization of three induced pluripotent stem cell lines (NUIGi046-A, NUIGi046-B, NUIGi046-C) from a 51-year-old healthy individual.

Derivation and characterization of two human induced pluripotent stem cell lines (NUIGi004-A) and (NUIGi012-A) from two patients with LQT2 disease.

Generation and characterization of three induced pluripotent stem cell lines (NUIGi047-A, NUIGi047-B, NUIGi047-C) from a 7-year-old healthy Caucasian male.

Derivation of four iPSC lines from a male ASD patient carrying a deletion in the middle coding region of NRXN1α gene (NUIGi039-A and NUIGi039-B) and a male sibling control (NUIGi040-A and NUIGi040-B).

Derivation of iPSC lines from two patients with autism spectrum disorder carrying NRXN1α deletion (NUIGi041-A, NUIG041-B; NUIGi045-A) and one sibling control (NUIGi042-A, NUIGi042-B).

Coupling of autism genes to tissue-wide expression and dysfunction of synapse, calcium signalling and transcriptional regulation.

Derivation of iPSC lines from three young healthy donors of Caucasian origin (NUIGi035-A; NUIGi036-A; NUIGi037-A).

Collaborators (4)

Timothy O’Brien

Amirhossein Jalali

Jing Wang

Jérôme Ruel

Make your next move.

Generation of three induced pluripotent stem cell lines from a patient with KCNQ2 developmental and epileptic encephalopathy as a result of the pathogenic variant c.881C > T; p.Ala294Val (NUIGi059-A, NUIGi059-B, NUIGi059-C) and 3 healthy controls (NUIGi060-A, NUIGi060-B, NUIGi060-C)