Sandra Franz

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Professor for Skin Regeneration

Leipzig University

Germany

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About

Professor Sandra Franz is a faculty member at Leipzig University in Germany, specializing in the field of Skin Regeneration. Her research primarily focuses on the mechanisms of wound healing and tissue repair, with recent articles exploring the roles of hyaluronan synthesis, macrophage differentiation, and inflammation in chronic wounds. Additionally, she investigates innovative therapeutic approaches, including the use of hydrogels and stem cell applications in tissue regeneration.

Recent Grants

Grant: Close

Innovative cell therapy to promote skin regeneration (ZellTWund)

Open Date: 2021-10-01

Close Date: 2024-09-01

Grant: Close

3D polymer matrix device for dual drug delivery and simultaneous treatment of acute malaria and malaria transmission

Open Date: 2021-07-01

Close Date: 2025-12-01

Grant: Close

Pathomechanisms of disturbed wound healing - consequences of S100A9 overexpression for wound healing

Open Date: 2020-01-01

Close Date:

Grant: Close

Regulation of macrophage polarisation by fibroblasts - impact for the wound healing response

Open Date: 2016-01-01

Close Date: 2020-12-01

Grant: Close

Regulation of macrophage polarisation by fibroblasts - impact for the wound healing response

Open Date: 2016-01-01

Close Date:

Articles (11)

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2024

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2024

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2024

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2023

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2022

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2022

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2021

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2021

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2021

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2020

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2020

Collaborators (3)

Anja Saalbach

Leipzig University

GERMANY

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Shohei Murakami

Assistant Professor

Tohoku University

JAPAN

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Federica Francesca Masieri

Associate Professor

University of Suffolk

UNITED KINGDOM

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Sandra Franz

Research Interests

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About

Recent Grants

Articles (11)

Dysregulated S100A9 Expression Impairs Matrix Deposition in Chronic Wounds

Dermal white adipose tissue derived IL-33 regulates interleukin 4/13 expression in myeloid cells during inflammation

Bone quality relies on hyaluronan synthesis – Insights from mice with complete knockout of hyaluronan synthase expression

Germ-free, carefree: injured skin uses IL-24 to kick-start repair independent of pathogen-recognition

Sulfated hyaluronic acid inhibits the hyaluronidase CEMIP and regulates the HA metabolism, proliferation and differentiation of fibroblasts

Overexpression of S100A9 in obesity impairs macrophage differentiation via TLR4-NFkB-signaling worsening inflammation and wound healing

Collagen/hyaluronan based hydrogels releasing sulfated hyaluronan improve dermal wound healing in diabetic mice via reducing inflammatory macrophage activity

Protease-Triggered Release of Stabilized CXCL12 from Coated Scaffolds in an Ex Vivo Wound Model

Modulation of macrophage functions by ECM-inspired wound dressings – a promising therapeutic approach for chronic wounds

Phagocytosis of Wnt inhibitor SFRP4 by late wound macrophages drives chronic Wnt activity for fibrotic skin healing

Autologous, Non-Invasively Available Mesenchymal Stem Cells from the Outer Root Sheath of Hair Follicle Are Obtainable by Migration from Plucked Hair Follicles and Expandable in Scalable Amounts

Collaborators (3)

Anja Saalbach

Shohei Murakami

Federica Francesca Masieri

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