Sangram Nag

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Karolinska Institutet

Sweden

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Utveckling av en avbildning markör för synaptiskt glykoprotein SV2C: en specifikt måltavla för synaptisk densitet vid Parkinsons sjukdom

Open Date: 2021-01-01

Close Date: 2023-12-31

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Collaborators (6)

António Paulo

PORTUGAL

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Lars Farde

Karolinska Institutet

SWEDEN

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Hans Ågren

SWEDEN

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Agneta Nordberg

Karolinska Institutet

SWEDEN

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Andre Martins

W3 Full Professor

University of Tübingen

GERMANY

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Jacqueline Borg

Karolinska Institutet

SWEDEN

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Sangram Nag

Research Interests

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Recent Grants

Articles (26)

Good Manufacturing Practice Validation and Radiation Dosimetry for the Clinical Application of a Novel α7-nAChR Radioligand: [<sup>11</sup>C]KIn83

Results of the first-in-human, randomized, double-blind, placebo-controlled, single- and multiple-ascending dose study of BIIB113 in healthy volunteers.

Imaging Proinflammatory Microglia in Parkinson Disease Using [11C]SMW139 PET: A Multicenter Study.

In vivo quantification of [11C]BIO-1819578 in non-human primates, a novel radioligand for O-GlcNAcase.

Test-retest properties of [11C]PXT012253 as a positron emission tomography (PET) radiotracer in healthy human brain: PET imaging of mGlu4.

PET imaging of antisense oligonucleotide distribution in rat and nonhuman primate brains using click chemistry.

Labeling of Bruton’s Tyrosine Kinase (BTK) Inhibitor [11C]BIO-2008846 in Three Different Positions and Measurement in NHP Using PET

Exploring the Interactions between two Ligands, UCB-J and UCB-F, and Synaptic Vesicle Glycoprotein 2 Isoforms

Automated radiosynthesis of mGluR5 PET tracer [18F]FPEB from aryl‐chloro precursor and validation for clinical application

Advancements in Microfluidic Cassette-Based iMiDEV™ Technology for Production of L-[11C]Methionine and [11C]Choline

Synthesis of [11C]BIIB104, an α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic-Acid-Positive Allosteric Modulator, and Evaluation of the Bio-Distribution in Non-Human Primate Brains Using Positron Emission Tomography

Pretargeted Imaging for In Vivo Assessment of ASO Therapy Delivery in Alzheimer’s Disease

Pretargeted Imaging for In Vivo Assessment of ASO Therapy Delivery in Alzheimer’s Disease

PET Evaluation of the Novel F-18 Labeled Reversible Radioligand [18F]GEH200449 for Detection of Monoamine Oxidase-B in the Non-Human Primate Brain

Development of a Novel [11C]CO-Labeled Positron Emission Tomography Radioligand [11C]BIO-1819578 for the Detection of O-GlcNAcase Enzyme Activity

Characterization of a Novel M4 PAM PET Radioligand [11C]PF06885190 in Nonhuman Primates (NHP)

Microfluidic-based production of [68Ga]Ga-FAPI-46 and [68Ga]Ga-DOTA-TOC using the cassette-based iMiDEV™ microfluidic radiosynthesizer.

P-073 Discovery of [18F]F-687-TCO: An Optimized Tracer for Pretargeted PET Imaging in the CNS

Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain.

Production of [11C]Carbon Labelled Flumazenil and L-Deprenyl Using the iMiDEV™ Automated Microfluidic Radiosynthesizer

Target occupancy study and whole-body dosimetry with a MAGL PET ligand [11C]PF-06809247 in non-human primates

Correction to “Development of 11C-Labeled ASEM Analogues for Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR)”

Development of 11C-Labeled ASEM Analogues for the Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR)

Decreased 5-HT1A binding in mild Alzheimer's disease-A positron emission tomography study

First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B

Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals

Collaborators (6)

António Paulo

Lars Farde

Hans Ågren

Agneta Nordberg

Andre Martins

Jacqueline Borg

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