Santos Manes

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Research Professor

Consejo Superior de Investigaciones Cientificas

Spain

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About

Dr. Santos Manes is a Research Professor at the Consejo Superior de Investigaciones Científicas in Spain. His research areas include the role of laminins in cancer pathobiology, the prognostic impact of immune cells in colorectal cancer, and the molecular classification of cancer through microRNA profiling. Dr. Manes has also explored the connections between metabolic processes and immune responses, contributing significantly to the understanding of tumor immunity and cognitive disorders.

Recent Grants

Grant: Close

Determinación de la firma molecular inducida por PD-1 en linfocitos T CD8+ humanos

Open Date: 2018-10-01

Close Date: 2019-07-01

Grant: Close

Reprogramacion del microambiente tumoral para aumentar la eficacia de la Inmunoterapia del cancer (TME-REP)

Open Date: 2018-01-01

Close Date: 2021-09-01

Grant: Close

Effect of the inhibitor NPO-2237 on tumorigenesis in mice

Open Date: 2017-11-01

Close Date: 2018-01-01

Grant: Close

Búsqueda de inhibidores de Calpaína 12 como potenciadores de la actividad citotóxica en linfocitos CD8

Open Date: 2017-07-01

Close Date:

Grant: Close

Inmunidad tumoral e inmunoterapia del cáncer -IMMUNOTHERCAN

Open Date: 2017-01-01

Close Date: 2021-12-01

Articles (14)

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2025

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (9)

Lydia Sorokin

Professor and Director

Westfälische Wilhelms-Universität Münster

GERMANY

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Amanda Cano

Head of Molecular Biology & Biomarkers program

SPAIN

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María Jesús Fernández Aceñero

Universidad Complutense de Madrid

SPAIN

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VEGA IRANZO GONZALEZ-CRUZ

Profesora Asociada Universitaria

University of Valencia

SPAIN

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Salvador Iborra

SPAIN

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Neris Michel Enamorado Escalona

Assistant Professor

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Rosa Noguera

SPAIN

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Elena Hernández‐García

SPAIN

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miguel quintela-fandino

Associate Professor

Universidad Autónoma de Madrid

SPAIN

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Santos Manes

Research Interests

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About

Recent Grants

Articles (14)

A laminin α4–CD8 + T cell axis shapes the prognostic impact of macrophages and regulatory T cells in early-stage colorectal cancer

The role of laminins in cancer pathobiology: a comprehensive review

Associations of plasma SMOC1 and soluble IL6RA levels with the progression from mild cognitive impairment to dementia

Biomechanical properties of laminins and their impact on cancer progression

Correlations between the NMR Lipoprotein Profile, <i>APOE</i> Genotype, and Cholesterol Efflux Capacity of Fasting Plasma from Cognitively Healthy Elderly Adults

Superoxide Dismutase-3 Downregulates Laminin α5 Expression in Tumor Endothelial Cells via the Inhibition of Nuclear Factor Kappa B Signaling

Molecular Classification of Colorectal Cancer by microRNA Profiling: Correlation with the Consensus Molecular Subtypes (CMS) and Validation of miR-30b Targets

DNGR-1 limits Flt3L-mediated antitumor immunity by restraining tumor-infiltrating type I conventional dendritic cells.

The Chemokine Receptor CCR5 Links Memory CD4<sup>+</sup> T Cell Metabolism to T Cell Antigen Receptor Nanoclustering.

Immunometabolism Modulation in Therapy

The Importance of Mitochondrial Pyruvate Carrier in Cancer Cell Metabolism and Tumorigenesis

Immuno-priming durvalumab with bevacizumab in HER2-negative advanced breast cancer: a pilot clinical trial

Extracellular Superoxide Dismutase, the Endothelial Basement Membrane, and the WNT Pathway: New Players in Vascular Normalization and Tumor Infiltration by T-Cells

SOD3 boosts T cell infiltration by normalizing the tumor endothelium and inducing laminin-α4.

Collaborators (9)

Lydia Sorokin

Amanda Cano

María Jesús Fernández Aceñero

VEGA IRANZO GONZALEZ-CRUZ

Salvador Iborra

Neris Michel Enamorado Escalona

Rosa Noguera

Elena Hernández‐García

miguel quintela-fandino

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