Sara Badr

Project Assistant Professor

University of Tokyo

Japan

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About

Sara Badr is a Project Assistant Professor at The University of Tokyo, Japan. Her research primarily focuses on pharmaceutical process design and operation, with recent studies addressing model-based design space exploration for drug synthesis and data-driven analysis of monoclonal antibodies. She has published various articles on topics such as anomaly detection in drug manufacturing and kinetic studies in pharmaceutical production processes.

Articles (21)

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2026

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2025

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2025

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2021

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2020

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2020

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2020

Collaborators (3)

Yusuke Hayashi

Assistant professor

University of Tokyo

JAPAN

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Hirokazu Sugiyama

University of Tokyo

JAPAN

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Eri Amasawa

Waseda University

JAPAN

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Sara Badr

Research Interests

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About

Articles (21)

Model-based disturbance-conscious design space exploration for drug substance flow synthesis using the Grignard reaction

Data-Driven Analysis of Monoclonal Antibody Charge Variants in Perfusion Cultures

Anomaly detection for drug product manufacturing considering data limitations and shifts: A case study on industrial freeze-dryers

Roles of mechanistic, data-driven, and hybrid modeling approaches for pharmaceutical process design and operation

Kinetic Study and Model-Based Design Space Determination for a Drug Substance Flow Synthesis Using an Amination Reaction via Nucleophilic Aromatic Substitution

Data-driven parameterization and development of mechanistic cell cultivation models in monoclonal antibody production processes: Shifts in cell metabolic behavior

Modeling of cell cultivation for monoclonal antibody production processes considering lactate metabolic shifts

Scenario Analysis of Vaccine Supply for COVID-19 in Japan Using Mathematical Models of Infectious Diseases

Impact of solvent selection on batch and flow syntheses for heterogeneous hydrogenation in drug substance manufacturing: A model-based analysis

Mechanistic insights into amination via nucleophilic aromatic substitution

Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes

Hybrid Modeling of an Active Pharmaceutical Ingredient Flow Synthesis in a Ring-Opening Reaction of an Epoxide with a Grignard Reagent

A systems evaluation model for the development of companion diagnostics and associated molecularly targeted therapies

Correction to “Cost–Benefit Analysis of Monoclonal Antibody Cultivation Scenarios in Terms of Life Cycle Environmental Impact and Operating Cost”

Data-Driven Approach toward Long-Term Equipment Condition Assessment in Sterile Drug Product Manufacturing

Hybrid Modeling of CHO Cell Cultivation in Monoclonal Antibody Production with an Impurity Generation Module

Integrated design of biopharmaceutical manufacturing processes: Operation modes and process configurations for monoclonal antibody production

Data-driven anomaly detection and diagnostics for changeover processes in biopharmaceutical drug product manufacturing

Multi-stage and multi-objective decision-support tool for biopharmaceutical drug product manufacturing: Equipment technology evaluation

A PSE perspective for the efficient production of monoclonal antibodies: integration of process, cell, and product design aspects

A graphical method for carbon dioxide emissions reduction in multi–product plants

Collaborators (3)

Yusuke Hayashi

Hirokazu Sugiyama

Eri Amasawa

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