Scott D. Gray-Owen

Professor

University of Toronto

Canada

Research Interests

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About

Scott D. Gray-Owen is a Professor at the University of Toronto in Canada. His research primarily focuses on vaccine development and immune responses, with recent articles exploring topics such as the immune response to meningococcal vaccines, SARS-CoV-2, and various bacterial infections. He has contributed significantly to the understanding of cellular immune responses and host factors related to viral infections, utilizing techniques such as CRISPR genetic screening and advanced imaging methods.

Articles (19)

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2025

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2020

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2020

Collaborators (16)

Maximilian Billmann

Assistant Professor

University Hospital Bonn

GERMANY

Scott D. Gray-Owen

Research Interests

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Articles (19)

Meningococcal vaccine 4CMenB elicits a robust cellular immune response that targets but is not consistently protective against Neisseria gonorrhoeae during murine vaginal infection

Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors

Identification of an Optimized Receptor-Binding Domain Subunit Vaccine against SARS-CoV-2.

Reverse vaccinology-based identification of a novel surface lipoprotein that is an effective vaccine antigen against bovine infections caused by Pasteurella multocida.

Immunoglobulin A nephropathy is characterized by anticommensal humoral immune responses.

Opposing roles of CLK SR kinases in controlling HIV-1 gene expression and latency.

<i>Akkermansia muciniphila</i> upregulates genes involved in maintaining the intestinal barrier function via ADP-heptose-dependent activation of the ALPK1/TIFA pathway.

Correlated STORM-homoFRET imaging reveals highly heterogeneous membrane receptor structures.

Two DNA vaccines protect against severe disease and pathology due to SARS-CoV-2 in Syrian hamsters.

Intranasal HD-Ad vaccine protects the upper and lower respiratory tracts of hACE2 mice against SARS-CoV-2

Challenges and Controversies Concerning Neisseria gonorrhoeae-Neutrophil Interactions in Pathogenesis

The Thiazole-5-Carboxamide GPS491 Inhibits HIV-1, Adenovirus, and Coronavirus Replication by Altering RNA Processing/Accumulation

Gonococcal Pelvic Inflammatory Disease: Placing Mechanistic Insights Into the Context of Clinical and Epidemiological Observations

Exploring the Ability of Meningococcal Vaccines to Elicit Mucosal Immunity: Insights from Humans and Mice

Detection of SARS-CoV-2 Viral Particles Using Direct, Reagent-Free Electrochemical Sensing.

Development of Antibiotics That Dysregulate the <i>Neisserial</i> ClpP Protease.

La pasteurisation à l’aide de la méthode de Holder appliquée au lait maternel provenant de donneuses permet d’inactiver le SRAS-CoV-2.

Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients.

The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of Helicobacter pylori in Neutrophils

Collaborators (16)

Maximilian Billmann

Emil Pai

Jun Liu

Sarah Crome

Rupert Kaul

Olga Rojas

Robert A. Batey

Leslie Parent

Nicolas Lapaque

Bryan Coburn

Marc-Antoine de La Vega

Hervé M. Blottière

Walid A. Houry

H Seifert

Vitor Hugo B. Serrão

Benoit Chabot

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