Scott Haake

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Assistant Professor

Vanderbilt University Medical Center

United States

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About

Scott Haake is an Assistant Professor at Vanderbilt University Medical Center in the United States. His research focuses on the mechanisms of renal cell carcinoma, including biomarker-informed strategies, immune landscape reprogramming, and the impact of obesity on tumor immunity. Recently, he has published articles investigating RNA biomarkers, integrin integration with cancer hallmarks, and epigenetic regulation of ribosomal RNA. His work aims to enhance understanding of tumor microenvironments and improve therapeutic approaches in oncology.

Recent Grants

Grant: Close

Constitutive Integrin Beta1 Signaling in Lung Cancer

Open Date: 2020-05-01

Close Date: 2025-04-30

Grant: Close

Endogenous Retrovirus Expression Drives Immunogenicity of Papillary Renal Cell Carcinoma

Open Date: 2019-10-01

Close Date: 2020-09-01

Grant: Close

SETD2 Regulates mRNA Translation: A Novel Mechanism Whereby SETD2 Mutations Promote Kidney Cancer Tumorigenesis

Open Date: 2019-04-01

Close Date: 2020-02-01

Grant: Close

Monitoring Disease Burden and Biology Using Tumor Cell-Free DNA in Metastatic Kidney Cancer

Open Date: 2018-10-01

Close Date: 2019-09-01

Grant: Close

Prognostic and Predictive Markers of Immunogenicity in Renal Cell Carcinoma

Open Date: 2017-09-01

Close Date: 2020-08-01

Articles (16)

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2020

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UNITED STATES

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Scott Haake

Research Interests

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About

Recent Grants

Articles (16)

Biomarker-informed care for patients with renal cell carcinoma

Refining the Tissue Source for Biomarker-based Approaches in Renal Cell Carcinoma

Sample Site Impacts RNA Biomarkers for Renal Cell Carcinoma

<i>VHL</i> loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis

Integrating integrins with the hallmarks of cancer

Endogenous retrovirus expression and its impact on tumor-infiltrating immune cells in papillary renal cell carcinoma

Epigenetic regulation of ribosomal RNA transcription and processing by the tumor suppressor SETD2

Initial screening efforts for the OPTIC RCC trial

Obesity induces PD-1 on macrophages to suppress anti-tumour immunity

Obesity induces PD-1 on macrophages to suppress anti-tumour immunity (Vol 630, pg 968, 2024)

Ligand-independent integrin β1 signaling supports lung adenocarcinoma development

Single-cell protein activity analysis identifies recurrence-associated renal tumor macrophages

Neoadjuvant pazopanib and molecular analysis of tissue response in renal cell carcinoma.

Hypoxia-induced epithelial to mesenchymal transition in cancer

PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma.

β1 Integrin regulates adult lung alveolar epithelial cell inflammation.

Collaborators (6)

xiande Liu

Brian Rini

Nancy Davis

Jonathan Kropski

Nidhi Sahni

Jeffrey C. Rathmell

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