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Sema Aygar

Has grant

Massachusetts General Hospital

United States

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Grant: Close

Generation and characterization of a NOTCH3 R133C-mutant iPSC line for CADASIL modeling

Open Date: 2021-11-01

Close Date: 2022-11-01

Articles (5)

Year:

2026

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Collaborators (4)

Robert Gardner

Research Assistant Professor

SUNY Upstate Medical University

UNITED STATES

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Nathan Tucker

Associate Professor

SUNY Upstate Medical University

UNITED STATES

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Morgan Miller

University of Michigan–Ann Arbor

UNITED STATES

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Mohamed Ariff Iqbal

University of Ottawa

CANADA

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Sema Aygar

Research Interests

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Recent Grants

Articles (5)

Ketogenic interventions enhance REM sleep in females and support memory in aged rats

Protective exercise responses in the dentate gyrus of Alzheimer's disease mouse model revealed with single-nucleus RNA-sequencing.

Generation of a human iPSC line with Notch3 R133C mutation by CRISPR/ Cas9: A tool for investigating CADASIL and therapeutic targets

NB-02 Protects Neurons and Astrocytes from Oligomeric Amyloid-β-Mediated Damage.

Monitoring hPSC Genomic Stability in the Chromosome 20q Region by ddPCR

Collaborators (4)

Robert Gardner

Nathan Tucker

Morgan Miller

Mohamed Ariff Iqbal

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