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Seth Grant

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Personal Chair in Molecular Neuroscience

University of Edinburgh

United Kingdom

Research Interests

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Professors in United Kingdom

Recent Grants

Grant: Close

The Human Brain Synaptome Project

Open Date: 2020-08-01

Close Date: 2024-07-01

Grant: Close

Synaptome imaging: development of synapse molecular imaging for neurology and psychiatry

Open Date: 2018-05-01

Close Date: 2019-02-01

Grant: Close

Single-synapse resolution molecular mapping of developmental trajectories across the whole mouse brain in monogenic models of autism

Open Date: 2018-04-01

Close Date: 2020-03-01

Grant: Close

Molecular synapse imaging technology and resources

Open Date: 2017-02-01

Close Date: 2020-02-01

Grant: Close

Molecular organization and dynamics of synapse diversity: novel genetic, imaging and computational approaches

Open Date: 2016-08-01

Close Date: 2020-07-31

Articles (20)

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Collaborators (16)

Kunhao Yuan

University of Edinburgh

UNITED KINGDOM

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Claire Shepherd

University of New South Wales

AUSTRALIA

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Yasunori Hayashi

Kyoto Prefectural University of Medicine

JAPAN

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Walter Kukull

Professor

Washington University in St. Louis

UNITED STATES

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Katsutaka Oishi

National Institute of Advanced Industrial Science and Technology (AIST)

JAPAN

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Maria Hauge Pedersen

Københavns Universitet

DENMARK

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Àlex Bayés

Principal Investigator

Institut de Recerca Sant Pau

SPAIN

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Melissa Murray

Associate Professor

Mayo Clinic Research Florida

UNITED STATES

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zhen qiu

Lecturer (Assistant Professor)

University of Dundee

UNITED KINGDOM

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Takeo Saneyoshi

Professor

Tokyo Institute of Technology

JAPAN

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Candace Adams

University of Edinburgh

UNITED KINGDOM

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Paul Anastasiades

University of Bristol

UNITED KINGDOM

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Takayuki Sassa

Hokkaido University

JAPAN

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Philipp Velicky

Head of Imaging Facility

Medical University of Vienna

AUSTRIA

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Gareth Miles

University of St. Andrews

UNITED KINGDOM

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Wanda Kukulski

University of Bern

SWITZERLAND

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Seth Grant

Research Interests

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Recent Grants

Articles (20)

Region- and Layer-Specific Glutamatergic Synapse Development in the Nascent Cortical Hierarchy

PRMix: Primary Region Mix Augmentation and Benchmark Dataset for Precise Whole Mouse Brain Anatomical Delineation

Dynamic structural plasticity facilitates the developmental assembly of cochlear inner hair cell ribbon synapses

Protein trafficking and synaptic demand configure complex and dynamic synaptome architectures of individual neurons.

Synapse types are spatially associated with regional hemodynamics in the mouse brain.

Accelerating biomedical discoveries in brain health through transformative neuropathology of aging and neurodegeneration

SynaptopathyDB integrates synaptic proteomes, genetic and phenotypic data to advance research on nervous system disorders.

The molecular infrastructure of glutamatergic synapses in the mammalian forebrain.

SV2A is expressed in synapse subpopulations in mouse and human brain: implications for PET radiotracer studies

Non-ionotropic signaling through the NMDA receptor GluN2B carboxy-terminal domain drives dendritic spine plasticity and reverses fragile X phenotypes.

FAM81A is a postsynaptic protein that regulates the condensation of postsynaptic proteins via liquid–liquid phase separation

Excitatory to inhibitory synaptic ratios are unchanged at presymptomatic stages in multiple models of ALS

Sleep maintains excitatory synapse diversity in the cortex and hippocampus

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment

Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex

MINFLUX fluorescence nanoscopy in biological tissue

3D Super-Resolution Imaging of PSD95 Reveals an Abundance of Diffuse Protein Supercomplexes in the Mouse Brain.

Synaptic expression of TAR-DNA-binding protein 43 in the mouse spinal cord determined using super-resolution microscopy

Dense 4D nanoscale reconstruction of living brain tissue

Pathway-Based Polygenic Risk Scores for Schizophrenia and Associations With Reported Psychotic-like Experiences and Neuroimaging Phenotypes in the UK Biobank

Collaborators (16)

Kunhao Yuan

Claire Shepherd

Yasunori Hayashi

Walter Kukull

Katsutaka Oishi

Maria Hauge Pedersen

Àlex Bayés

Melissa Murray

zhen qiu

Takeo Saneyoshi

Candace Adams

Paul Anastasiades

Takayuki Sassa

Philipp Velicky

Gareth Miles

Wanda Kukulski

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