Seung-Taek Lee

Professor

Yonsei University

South Korea

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About

Seung-Taek Lee is a Professor at Yonsei University in South Korea. His research focuses on cancer biology, extracellular matrix integrity, and fibroblast function, as evidenced by his recent articles on oncogenic mechanisms in breast cancer and the roles of various proteins in cellular signaling pathways. His work includes studies on PTK7, HSP47, and SOD3, contributing to the understanding of tumor microenvironments and fibroblast behavior.

Articles (12)

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2025

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2024

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2020

Collaborators (2)

Dong Hun Lee

Seoul National University College of Medicine

SOUTH KOREA

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Ho Lee

Professor

SOUTH KOREA

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Seung-Taek Lee

Research Interests

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Articles (12)

Anti-PTK7 Monoclonal Antibodies Suppresses Oncogenic Phenotypes in Cellular and Xenograft Models of Triple-Negative Breast Cancer

HSP47 Increases the Expression of Type I Collagen in Fibroblasts through IRE1α Activation, XBP1 Splicing, and Nuclear Translocation of β-Catenin

LRG1 Promotes ECM Integrity by Activating the TGF-β Signaling Pathway in Fibroblasts

SPARC Is Highly Expressed in Young Skin and Promotes Extracellular Matrix Integrity in Fibroblasts via the TGF-β Signaling Pathway

Knockdown of PTK7 Reduces the Oncogenic Potential of Breast Cancer Cells by Impeding Receptor Tyrosine Kinase Signaling

Anti-PTK7 Monoclonal Antibodies Exhibit Anti-Tumor Activity at the Cellular Level and in Mouse Xenograft Models of Esophageal Squamous Cell Carcinoma

Anti-PTK7 Monoclonal Antibodies Inhibit Angiogenesis by Suppressing PTK7 Function

Expression of Polyamine Oxidase in Fibroblasts Induces MMP-1 and Decreases the Integrity of Extracellular Matrix

Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells

SOD3 Suppresses the Expression of MMP-1 and Increases the Integrity of Extracellular Matrix in Fibroblasts

PTK7, a Catalytically Inactive Receptor Tyrosine Kinase, Increases Oncogenic Phenotypes in Xenograft Tumors of Esophageal Squamous Cell Carcinoma KYSE-30 Cells

Effects of Tenascin C on the Integrity of Extracellular Matrix and Skin Aging

Collaborators (2)

Dong Hun Lee

Ho Lee

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