Shan Lin

Assistant Professor

Seattle Children's Hospital

United States

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About

Shan Lin is an Assistant Professor at Seattle Children's Hospital in the United States. His research focuses on leukemia, specifically the chromatin profiles in MLL-rearranged acute lymphoblastic leukemia and therapeutic vulnerabilities in acute myeloid leukemia. His recent publications include investigations into transcriptional activity related to Ewing sarcoma and targeted therapies for pediatric patients with high-risk leukemias.

Articles (9)

Year:

2025

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Collaborators (5)

Jennifer McNeer

Professor

University of Utah

UNITED STATES

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Nastassja Scheidegger

University Children's Hospital Zurich

SWITZERLAND

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Yusuke Tarumoto

助教 / Assistant Professor

Kyoto University

JAPAN

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ALEXANDRE PUISSANT

Principal Investigator, Tenured Associate Professor

FRANCE

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Jana Ellegast

Assistant Professor for Translational Oncology; Attending Physician

University of Zurich

SWITZERLAND

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Shan Lin

Research Interests

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Articles (9)

Fusion-specific chromatin profiles mediate transcriptional heterogeneity in MLL-rearranged acute lymphoblastic leukemia

The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.

Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia.

Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts

An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML

Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-risk Leukemias: A Report from the LEAP Consortium.

TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma.

STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma.

Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo

Collaborators (5)

Jennifer McNeer

Nastassja Scheidegger

Yusuke Tarumoto

ALEXANDRE PUISSANT

Jana Ellegast

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