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Sheng Chen

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Professor/HoD

The Hong Kong Polytechnic University

Hong Kong

Research Interests

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Professors in Microbiology

Recent Grants

Grant: Close

Development of novel inhibitors targeting the resistance mechanisms of clinical superbugs

Open Date: 2017-07-01

Close Date: 2020-07-01

Grant: Close

Re-defining the molecular basis of carbapenem resistance in clinical Acinetobacter baumannii isolates

Open Date: 2016-07-01

Close Date: 2018-07-01

Grant: Close

Total synthesis and medicinal chemistry of cyclic peptide-based antibacterial compounds: an integrative programme for novel antibiotic development; Collaborative Research Fund

Open Date: 2016-06-01

Close Date: 2019-06-01

Grant: Close

Development of novel tridenate inhibitors targeting to active site residues and Zin ions of NDM-1

Open Date: 2015-07-01

Close Date: 2017-07-01

Grant: Close

Characterization the role of OqxAB in Salmonella virulence and antimicrobial resistance.

Open Date: 2015-07-01

Close Date: 2017-07-01

Articles (20)

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2027

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2026

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2025

Collaborators (3)

Guan Yang

City University of Hong Kong

HONG KONG

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Yu Huang

Jeanie Hu Professor of Biomedical Sciences

City University of Hong Kong

HONG KONG

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Jin Wang

Research Associate

McGill University

CANADA

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ApplyKite TwinLearns as you apply

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Sheng Chen

Research Interests

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Recent Grants

Articles (20)

Combining polydopamine deposition and CsPbBr3@SiO2 QDs enables ultrasensitive and broadly specific monoclonal antibody-based in situ Salmonella imaging detection

Metagenomic and culture‐based insights into host and plasmid contexts of high‐risk ARGs in poultry farm environments

Drug‐Loaded Passive Cooling Hydrogels for Synergistic Thermal and Anti‐Inflammatory Regulation of Skin Wounds

Rapid Broad-Spectrum Colorimetric Detection of Bacteria Using Polylysine-Mediated Gold Nanoparticle Aggregation

Beyond dormancy: Active DNA repair and protein synthesis drive antibiotic tolerance and enable synergistic eradication

Population genomics uncovers global distribution, antimicrobial resistance, and virulence factors of Streptococcus suis

Single‐Cell Atlas Reveals Neutrophil Heterogeneity in Hypervirulent Klebsiella pneumoniae Infection‐Induced Sepsis

Long-Lived, Nonenzymatic Signal Generation Chemiluminescence Immunoassay for Pretreatment-Free Detection of Lincomycin in Milk

The New Delhi Metallo-β-lactamase-1 Covalent Inhibitors Derived from Cephalexin Effectively Reverse Meropenem Resistance

Cytokine-driven PANoptosis of alveolar macrophages mediated by STAT1 underlies acute lung injury in hypervirulent Klebsiella pneumoniae infection

Novel Antimicrobial Nano Bacteriocin

Molecular surveillance of foodborne bacterial pathogens and resistome in food products from Hong Kong

Proposal for the nomenclature of tmexCD-toprJ-like gene clusters

Hydrogenase-mediated metabolic functions contribute to formation of bacterial antibiotic tolerance through regulating redox homeostasis and maintaining membrane potential

Exercised gut microbiota improves vascular and metabolic abnormalities in sedentary diabetic mice through gut‒vascular connection

Structure-Directed Optimization of Ebselen Derivatives as Potent NDM-1 Inhibitors Reverses Meropenem Resistance

Genomic and phenotypic analysis of virulence, antimicrobial resistance, and transmission routes of Vibrio vulnificus from food and clinical sources in China

IncFIBK/FIIK conjugative iuc3-carrying virulence plasmids of clinical hypervirulent Klebsiella pneumoniae are multi-drug resistant

LTX-315 is a novel broad-spectrum antimicrobial peptide against clinical multidrug-resistant bacteria

Ultrasensitive monoclonal antibody-based Salmonella detection through fluorescence single bacterial cell imaging selectively enhanced by tyramide signal amplification

Collaborators (3)

Guan Yang

Yu Huang

Jin Wang

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