Shevin Jacob

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Liverpool School of Tropical Medicine

United Kingdom

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Dr. Shevin Jacob is a Reader at the Liverpool School of Tropical Medicine in the United Kingdom. His research focuses on emerging infectious diseases, particularly sepsis and its management in resource-limited settings. Recent publications include topics on the challenges of clinical management in outbreak situations and the development of early warning systems for severe maternal outcomes. Dr. Jacob actively contributes to the understanding of infectious disease epidemiology through various thematic studies and international consensus efforts.

Recent Grants

Grant: Open

Sub-Saharan Africa ConsorTium for the Advancement of Innovative Research and Care in Sepsis (STAIRS)

Open Date: 2023-08-01

Close Date: 2028-07-01

Grant: Close

Strengthening CAre in collaboration with People with lived Experience of psychosis in Uganda (SCAPE-U)

Open Date: 2022-04-01

Close Date: 2025-03-31

Grant: Close

AGILE: Seamless Phase I/IIa Platform for the Rapid Evaluation of Candidates for COVID-19 treatment

Open Date: 2021-02-01

Close Date: 2023-01-31

Grant: Close

Preparation for the Randomised Evaluation of a VItamin C bundle for Sepsis Treatment in Africa (REVISTA-Prep)

Open Date: 2019-08-31

Close Date: 2020-08-30

Grant: Close

Preventing Hospital Re-admissions for People with Severe Mental Illness in East Africa (PRISM)

Open Date: 2018-06-30

Close Date: 2019-09-29

Shevin Jacob

Research Interests

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Recent Grants

Articles (22)

Delayed correct diagnoses in emerging disease outbreaks: historical patterns and lessons for contemporary responses.

'Involve those who are managing these outbreaks': stakeholders' perspectives on the barriers and facilitators to the implementation of clinical management guidelines for high-consequence infectious diseases in Uganda-a thematic network analysis.

Adaptive Design for Phase II/III Platform Trial of Lassa Fever Therapeutics.

The Sepsis Chain of Survival

Early warning systems for identifying severe maternal outcomes: findings from the WHO global maternal sepsis study: findings from the WHO global maternal sepsis study

Proposed Framework for Conducting Clinically Relevant Translational Biomarker Research for the Diagnosis, Prognosis and Management of Sepsis

Pediatric post-discharge mortality in resource-poor countries: a systematic review and meta-analysis

Core sepsis-related competencies for medical students: an international consensus by Delphi technique

Management of adult sepsis in resource-limited settings: global expert consensus statements using a Delphi method.

Vaccines for preventing Ebola virus disease

Caregivers’ and nurses’ perceptions of the Smart Discharges Program for children with sepsis in Uganda: A qualitative study

Ebola disease outbreak caused by the Sudan virus in Uganda, 2022: a descriptive epidemiological study: a descriptive epidemiological study

Drivers of Resistance in Uganda and Malawi (DRUM): a protocol for the evaluation of One-Health drivers of Extended Spectrum Beta Lactamase (ESBL) resistance in Low-Middle Income Countries (LMICs)

Risk factors, temporal dependence, and seasonality of human ESBL-producing E. coli and K. pneumoniae colonisation in Malawi

Investigating One Health risks for human colonisation with extended spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae in Malawian households

YouBelong Home: A Ugandan Community Mental Health Intervention

Pathogen Detection Using Metagenomic Next-Generation Sequencing of Plasma Samples from Patients with Sepsis in Uganda

Pediatric post-discharge mortality in resource-poor countries: A protocol for an updated systematic review and meta-analysis

Standard of care for viral haemorrhagic fevers (VHFs): a systematic review of clinical management guidelines for high-priority VHFs

Equitable endotyping is essential to achieve a global standard of precise, effective, and locally-relevant sepsis care

Facilitating high quality acute care in resource-constrained environments: Perspectives of patients recovering from sepsis, their caregivers and healthcare workers in Uganda and Malawi

Recognising Sepsis as a Health Priority in Sub-Saharan African Country: Learning Lessons from Engagement with Gabon’s Health Policy Stakeholders

Collaborators (17)

Stefan Schilling

David Cappo

Tom Fletcher

Fiona Verity

Gilbert Greub

Dania Dahmash

Niranjan Kissoon

Nicola Elviss

derek cocker

Effrossyni Gkrania-Klotsas

Adam Roberts

Tracy Morse

Hung-Yuan Cheng

David M. Goldfarb

Peter Horby

Thomas Edwards

Laura Bonnett

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