Shigeo Ohno

Research Professor

Juntendo University

Japan

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About

Shigeo Ohno is a Research Professor at Juntendo University in Japan. His research focuses on various aspects of cellular signaling and stem cell biology, including the implications of PKCλ and ALDH1A3 in pancreatic ductal adenocarcinoma (PDAC) prognosis. Additionally, he investigates the regulation of neural precursor cell expansion and epithelial cell polarity through proteins such as PAR3 and Shank2.

Articles (4)

Year:

2023

Year:

2022

Year:

2020

Year:

2020

Collaborators (3)

Kana Furukawa

Assistant Professor

Osaka University

JAPAN

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Yohsuke Harada

University of Tokyo

JAPAN

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Hidetake Kurihara

Vice-president, Professor

JAPAN

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Shigeo Ohno

Research Interests

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Articles (4)

High expression of PKCλ and ALDH1A3 indicates a poor prognosis, and PKCλ is required for the asymmetric cell division of ALDH1A3-positive cancer stem cells in PDAC

PAR3 restricts the expansion of neural precursor cells by regulating hedgehog signaling

Phosphorylation and dephosphorylation of Ser852 and Ser889 control clustering, localization, and function of PAR3

Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity

Collaborators (3)

Kana Furukawa

Yohsuke Harada

Hidetake Kurihara

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