Shigeyuki Yokoyama

Head of RIKEN Yokoyama Laboratory

Japan

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Shigeyuki Yokoyama is the Head of RIKEN Yokoyama Laboratory in Japan. His research focuses on protein structure and function, particularly in relation to intraflagellar transport, glioblastoma therapy, and autophagy mechanisms. Recent publications highlight his work on the structural analysis of protein interfaces and the identification of biomarkers for atherosclerosis and cancer.

Articles (19)

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2024

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2023

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2023

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2023

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2023

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2022

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2022

Collaborators (4)

Takanori Iwata

Professor and Chair

Tokyo Medical and Dental University

JAPAN

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Takaki Hiwasa

Chiba University

JAPAN

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Tomoyasu Hirose

Professor

Kitasato University

JAPAN

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Toru Kondo

Professor

Hokkaido University

JAPAN

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Shigeyuki Yokoyama

Research Interests

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Articles (19)

Site-specific photo-crosslinking of Hsc70 with the KFERQ pentapeptide motif in a chaperone-mediated autophagy and microautophagy substrate in mammalian cells

<SUP>1</SUP>H, <SUP>13</SUP>C, and <SUP>15</SUP>N resonance assignments and solution structure of the N-terminal divergent calponin homology (NN-CH) domain of human intraflagellar transport protein 54

EVA1-antibody drug conjugate is a new therapeutic strategy for eliminating glioblastoma-initiating cells

EVA1-antibody drug conjugate is a new therapeutic strategy for eliminating glioblastoma-initiating cells

Protein-Protein Interface Identification by Site-Specific Photo-Cross-linking/Cleavage in Mammalian Cells

Protein‐Protein Interface Identification by Site‐Specific Photo‐Cross‐linking/Cleavage in Mammalian Cells

Serum anti‑KIAA0513 antibody as a common biomarker for mortal atherosclerotic and cancerous diseases

Serum anti‑KIAA0513 antibody as a common biomarker for mortal atherosclerotic and cancerous diseases

Site-specific photo-crosslinking of Hsc70 with the KFERQ pentapeptide motif in a chaperone-mediated autophagy and microautophagy substrate in mammalian cells

Structural basis for the effects of Ser387 phosphorylation of MgcRacGAP on its GTPase-activating activities for CDC42 and RHOA

A Potent PDK4 Inhibitor for Treatment of Heart Failure with Reduced Ejection Fraction

Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic Archaeon ISO4-G1 and Its Structure-Based Engineering for Highly-Productive Cell-Free Genetic Code Expansion with Non-Canonical Amino Acids

Crystal Structure of Pyrrolysyl-tRNA Synthetase from a Methanogenic Archaeon ISO4-G1 and Its Structure-Based Engineering for Highly-Productive Cell-Free Genetic Code Expansion with Non-Canonical Amino Acids

Contributions of the N-terminal flanking residues of an antigenic peptide from the Japanese cedar pollen allergen Cry j 1 to the T-cell activation by HLA-DP5

Crystal structure analysis of pyrrolidone carboxyl peptidase from Thermus thermophilus

Site-specific photo-crosslinking/cleavage for protein-protein interface identification reveals oligomeric assembly of lysosomal-associated membrane protein type 2A in mammalian cells

Structural basis for the dual GTPase specificity of the DOCK10 guanine nucleotide exchange factor

Crystal structure analysis and molecular dynamics simulations of arginase from Thermus thermophilus

H-1, C-13 and N-15 resonance assignments and solution structures of the two RRM domains of Matrin-3

Collaborators (4)

Takanori Iwata

Takaki Hiwasa

Tomoyasu Hirose

Toru Kondo

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