Shiv Gupta

Assistant Professor and Research Associate

Mayo Clinic Minnesota

United States

Research Interests

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Shiv Gupta is an Assistant Professor and Research Associate at Mayo Clinic Research in Minnesota, USA. His research focuses on the pharmacokinetics and therapeutic effects of antibody-drug conjugates in glioblastoma, exploring topics such as bystander effects, ATM inhibition, and in vivo efficacy of targeted therapies. Gupta's recent articles contribute significantly to understanding the challenges of treating EGFR-amplified glioblastoma and the role of cellular mechanisms in tumor response.

Articles (4)

Year:

2026

Year:

2024

Year:

2024

Year:

2021

Collaborators (2)

Daniel Laverty

Assistant Professor

Lehigh University

UNITED STATES

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Sonia Jain

Research associate

Mayo Clinic

UNITED STATES

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Shiv Gupta

Research Interests

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Articles (4)

Divergent Roles of Canonical and Non-Canonical Mismatch Repair in Regulating Temozolomide Sensitivity in Glioblastoma

Bystander Effects, Pharmacokinetics, and Linker-Payload Stability of EGFR-Targeting Antibody-Drug Conjugates Losatuxizumab Vedotin and Depatux-M in Glioblastoma Models

ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma

In Vivo Efficacy of Tesevatinib in EGFR-Amplified Patient-Derived Xenograft Glioblastoma Models May Be Limited by Tissue Binding and Compensatory Signaling

Collaborators (2)

Daniel Laverty

Sonia Jain

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