Siegfried Janz

Professor & Multiple Myeloma Endowed Chair

Medical College of Wisconsin

United States

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Dr. Siegfried Janz is a Professor and the Multiple Myeloma Endowed Chair at the Medical College of Wisconsin, USA. His research focuses on the molecular and immunological factors affecting survival in multiple myeloma, as well as the immune microenvironment's changes during plasma cell tumor development. His recent work includes investigations into genetic determinants of disease progression and clinical outcomes related to therapies such as CAR-T and hematopoietic cell transplantation.

Articles (14)

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2025

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2022

Collaborators (6)

Aniko Szabo

UNITED STATES

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Jing Dong

Medical College of Wisconsin

UNITED STATES

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Carolina Schinke

UNITED STATES

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Sergio Giralt

Chief Attending, Adult BMT Service

Memorial Sloan Kettering Cancer Center

UNITED STATES

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Cody Ashby

Assistant Professor

University of Arkansas for Medical Sciences

UNITED STATES

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Anita D'Souza

UNITED STATES

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Siegfried Janz

Research Interests

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Articles (14)

Molecular and Immunological Determinants of Long-Term Survival in Multiple Myeloma

Changes in the immune microenvironment during plasma cell tumor development in the IL6Myc mouse model of human multiple myeloma

Identification of novel loci for multiple myeloma when comparing with its precursor condition monoclonal gammopathy of unknown significance

Blood and marrow transplant within 4 weeks of SARS-CoV-2 infection is associated with increased risk of mortality: a National COVID Cohort Collaborative (N3C) Study

A timeline of genetic variant enrichment: from multiple myeloma diagnosis to myeloma-associated myeloid malignancy

Increased CXCL10 is seen at 1-year after autologous hematopoietic cell transplantation in multiple myeloma patients on maintenance lenalidomide therapy

A gene signature can predict risk of MGUS progressing to multiple myeloma

Clinical outcome of patients with relapsed refractory multiple myeloma listed for BCMA directed commercial CAR-T therapy

DNA methylation in circulating leukocytes is a novel biomarker in multiple myeloma

NAT10 promotes cell proliferation by acetylating CEP170 mRNA to enhance translation efficiency in multiple myeloma

Socioeconomic disadvantage contributes to ethnic disparities in multiple myeloma survival: a matched cohort study

Critical Role for Cap-Independent c-MYC Translation in Progression of Multiple Myeloma

Black patients with multiple myeloma have better survival than white patients when treated equally: a matched cohort study

Corneal toxicity with belantamab mafodotin: Multi-institutional real-life experience

Collaborators (6)

Aniko Szabo

Jing Dong

Carolina Schinke

Sergio Giralt

Cody Ashby

Anita D'Souza

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