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Silvia Maioli

Karolinska Institutet

Sweden

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Research Interests

Neurology

60%

Systems Neuroscience

20%

Cholesterol Metabolism

50%

Neurodegenerative Disease

50%

Neuroprotection

30%

Neuroinflammation

30%

Cohort Study

20%

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Articles20

Association of Plasma Fatty Acid Profile With Trajectory of Multimorbidity and Mortality: A Community-Based Longitudinal Study

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Year:

2025

Elevated 24-hydroxycholesterol levels counteract okadaic acid-induced tau hyperphosphorylation and neuronal morphology impairment.

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2025

Reactive Astrocytes with Reduced Function of Glutamate Transporters in the AppNL-G-F Knock-in Mice.

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2025

ERβ mediates sex-specific protection in the App-NL-G-F mouse model of Alzheimer's disease.

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2025

Atrophy trajectories in Alzheimer's disease: how sex matters.

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2025

Commonly prescribed multi-medication therapies exert sex-specific effects on Alzheimer's disease pathology and metabolomic profiles in AppNL-G-F mice: Implications for personalized therapeutics in aging.

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2025

Antidepressant use and cognitive decline in patients with dementia: a national cohort study.

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2025

Medications and cognitive decline in Alzheimer's disease: Cohort cluster analysis of 15,428 patients.

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2025

CYP46A1-mediated cholesterol turnover induces sex-specific changes in cognition and counteracts memory loss in ovariectomized mice

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2024

Dynamic microglia alterations associate with hippocampal network impairments: A turning point in amyloid pathology progression.

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2024

Impaired astrocytic synaptic function by peripheral cholesterol metabolite 27-hydroxycholesterol.

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2024

27‐hydroxycholesterol promotes oligodendrocyte maturation: Implications for hypercholesterolemia‐associated brain white matter changes

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2023

Alzheimer’s disease biomarker profiling in a memory clinic cohort without common comorbidities

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2023

Statins and cognitive decline in patients with Alzheimer's and mixed dementia: a longitudinal registry-based cohort study.

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2023

Different effects of CYP27A1 and CYP7B1 on cognitive function: Two mouse models in comparison.

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2023

SIRT2 Inhibition Rescues Neurodegenerative Pathology but Increases Systemic Inflammation in a Transgenic Mouse Model of Alzheimer's Disease.

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2023

A metagenomic study of gut viral markers in amyloid-positive Alzheimer's disease patients.

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Year:

2023

Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in AppNL-G-F/NL-G-F mice

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2022

Brain Renin–Angiotensin System as Novel and Potential Therapeutic Target for Alzheimer’s Disease

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2021

Chronic polypharmacy impairs explorative behavior and reduces synaptic functions in young adult mice.

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Year:

2020

Collaborators12

Per Nilsson

Team leader, Assoc Prof

Karolinska Institutet

SWEDEN

Mukesh Varshney

Karolinska Institutet

SWEDEN

Eric Westman

Professor

Karolinska Institutet-Huddinge Campus

SWEDEN

Luis Enrique Arroyo-Garcia

Assistant Professor

Karolinska Institutet

SWEDEN

Hong Xu

Karolinska Institutet

SWEDEN

Michelle Dunk

Karolinska Institutet

SWEDEN

Vilma Alanko

Karolinska Institutet

SWEDEN

Weili Xu

Karolinska Institutet

SWEDEN

Raúl Loera-Valencia

Karolinska Institutet

SWEDEN

Patricia Rodriguez-Rodriguez

Karolinska Institutet

SWEDEN

Eduardo D. Martín

Instituto de Neurobiología Ramón y Cajal

SPAIN

Elena Alberdi

University of the Basque Country

SPAIN

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