Simeon Santourlidis

Director Epigenetics Core Laboratory/ Professor Dr.

Heinrich-Heine-Universität Düsseldorf Medizinische Fakultät

Germany

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Professor Dr. Simeon Santourlidis serves as the Director of the Epigenetics Core Laboratory at Heinrich-Heine-Universität Düsseldorf Medizinische Fakultät in Germany. His research primarily focuses on epigenetics, cancer progression, and the roles of non-receptor tyrosine kinases in tumor dynamics. He has authored and co-authored numerous articles examining topics such as the epigenetic aspects of mammalian developmental evolution and the therapeutic targeting of the tumor microenvironment in melanoma treatment.

Articles (17)

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2025

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2024

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2024

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2024

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2022

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2022

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2022

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2022

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2020

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2020

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2020

Collaborators (3)

Naji Kharouf

Professor (Assoc.)

University of Strasbourg

FRANCE

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Mohamed Hassan

University of Strasbourg

FRANCE

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Florence Carrouel

Université Claude Bernard Lyon 1

FRANCE

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Simeon Santourlidis

Research Interests

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Articles (17)

Phylo-Epigenetic Conservation and CpG Erosion in OCT4, SOX2, and hTERT Intragenic CpG Islands: A Waddingtonian Perspective on Mammalian Developmental Evolution

Non-Receptor Tyrosine Kinases: Their Structure and Mechanistic Role in Tumor Progression and Resistance

<i>hTERT</i> Epigenetics Provides New Perspectives for Diagnosis and Evidence-Based Guidance of Chemotherapy in Cancer

CD133-Dependent Activation of Phosphoinositide 3-Kinase /AKT/Mammalian Target of Rapamycin Signaling in Melanoma Progression and Drug Resistance

Mechanisms of Melanoma Progression and Treatment Resistance: Role of Cancer Stem-like Cells

Phylo-Epigenetics in Phylogeny Analyses and Evolution

Epigenetics Meets CAR-T-Cell Therapy to Fight Cancer

Tumor Microenvironment as a Therapeutic Target in Melanoma Treatment

Induction of Antimicrobial Protein S100A15 Expression by Oral Microbial Pathogens Is Toll-like Receptors-Dependent Activation of c-Jun-N-Terminal Kinase (JNK), p38, and NF-κB Pathways

Consistent DNA Hypomethylations in Prostate Cancer

Differential DNA Methylation of THOR and hTAPAS in the Regulation of hTERT and the Diagnosis of Cancer

Methyl Group Metabolism in Differentiation, Aging, and Cancer

Phyloepigenetics

Epigenetics in the Diagnosis and Therapy of Malignant Melanoma

Aging-associated distinctive DNA methylation changes of LINE-1 retrotransposons in pure cell-free DNA from human blood.

Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1

Melanoma stem cell maintenance and chemo-resistance are mediated by CD133 signal to PI3K-dependent pathways

Collaborators (3)

Naji Kharouf

Mohamed Hassan

Florence Carrouel

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