Simon-Pierre Gravel

Assistant professor

Université de Montréal

Canada

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Simon-Pierre Gravel is an Assistant Professor at the University of Montreal, Canada. His research areas focus on mitochondrial dynamics, epidermal physiology, and the therapeutic potential of mRNA nanocarriers. Recent publications highlight his work on phenotype switching in response to PLK1 inhibitors and the role of PGC-1s in keratinocyte behavior, as well as the expression of mitochondrial biogenesis modulators in melanoma.

Articles (4)

Year:

2025

Year:

2023

Year:

2022

Year:

2022

Collaborators (1)

Etienne Audet-Walsh

Assistant professor

Laval University

CANADA

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Simon-Pierre Gravel

Research Interests

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Articles (4)

Mitochondrial signatures shape phenotype switching and apoptosis in response to PLK1 inhibitors

PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation

Low expression of PGC-1β and other mitochondrial biogenesis modulators in melanoma is associated with growth arrest and the induction of an immunosuppressive gene expression program dependent on MEK and IRF-1.

Current knowledge on the tissue distribution of mRNA nanocarriers for therapeutic protein expression

Collaborators (1)

Etienne Audet-Walsh

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