Simone Bersini

Assistant Professor

Università del Salento

Switzerland

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Simone Bersini is an Assistant Professor at Università della Svizzera italiana. Her research focuses on endothelial-mesenchymal transition, microphysiological systems, and the study of drug resistance in breast cancer metastasis. Recent publications include investigations into angiogenesis in aging and inflammation, as well as innovative in vitro models for studying cancer cell interactions. She aims to enhance the understanding of metastatic processes and develop new therapeutic strategies.

Articles (14)

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2024

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2024

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2020

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2020

Collaborators (4)

Carmen Ghilardi

Head of the Unit of Molecular Anticancer Therapy

Istituto di Ricerche Farmacologiche Mario Negri IRCCS

ITALY

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MARIA LAURA COSTANTINO

Full Professor in Industrial Bioengineering

Politecnico di Milano

ITALY

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LUCA POSSENTI

Fondazione IRCCS Istituto Nazionale dei Tumori

ITALY

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Florencia Cidre-Aranaz

Deputy Head of Division & Team Leader

German Cancer Research Center (DKFZ)

GERMANY

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Simone Bersini

Research Interests

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Articles (14)

Endothelial‐mesenchymal transition in skeletal muscle: Opportunities and challenges from 3D microphysiological systems

Complex or not too complex? One size does not fit all in next generation microphysiological systems.

Differential angiogenesis of bone and muscle endothelium in aging and inflammatory processes

In vitro models of breast cancer bone metastasis: analyzing drug resistance through the lens of the microenvironment.

A microfluidic model of human vascularized breast cancer metastasis to bone for the study of neutrophil-cancer cell interactions

Beyond Static Pipes: Mechanisms and In Vitro Models of Vascular Aging

Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma

Radiobiological Studies of Microvascular Damage through In Vitro Models: A Methodological Perspective

A microphysiological early metastatic niche on a chip reveals how heterotypic cell interactions and inhibition of integrin subunit β<sub>3</sub>impact breast cancer cell extravasation

Engineering the early bone metastatic niche through human vascularized immuno bone minitissues

Erratum: A microphysiological early metastatic niche on a chip reveals how heterotypic cell interactions and inhibition of integrin subunit β<sub>3</sub>impact breast cancer cell extravasation (Lab Chip (2021) DOI: 10.1039/d0lc01011a)

The driving role of the Cdk5/Tln1/FAK<sup>S732</sup> axis in cancer cell extravasation dissected by human vascularized microfluidic models

Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and hutchinson-gilford progeria syndrome

Direct reprogramming of human smooth muscle and vascular endothelial cells reveals defects associated with aging and Hutchinson-Gilford progeria syndrome

Collaborators (4)

Carmen Ghilardi

MARIA LAURA COSTANTINO

LUCA POSSENTI

Florencia Cidre-Aranaz

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