Simone Kosol

Lecturer (Biochemistry)

Medical School Berlin

Germany

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Simone Kosol is a Lecturer in Biochemistry at MSB Medical School Berlin, Germany. Her research focuses on antibacterial drug development and the mechanisms of antimicrobial resistance, as highlighted in her recent articles. She has contributed to the understanding of antibiotic derivatives, cyclic peptides, and the interaction of proteins related to gene expression and cytoskeletal activity.

Articles (10)

Year:

2025

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (7)

Arnar Sigurdsson

Humboldt-Universität zu Berlin Institut für Chemie

GERMANY

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Roderich D. Süssmuth

GERMANY

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Bettina G. Keller

Professor for Theoretical Chemistry

Freie Universität Berlin

GERMANY

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Alessandro Piai

Senior Research Investigator, Head of NMR

IRBM Science Park

ITALY

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Józef Lewandowski

Professor

University of Warwick

UNITED KINGDOM

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Fereshteh Ghazisaeedi

Freie Universität Berlin

GERMANY

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Isabella Felli

Associate Professor

University of Arkansas - Rome Center

ITALY

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Simone Kosol

Research Interests

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Articles (10)

Synthesis of Derivatives of the Antibiotic Albicidin: The N-Terminal Fragment as Key to Control Potency and Resistance Mediated by the Binding Protein AlbA.

Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research.

Discovery of the lanthipeptide curvocidin and structural insights into its trifunctional synthetase CuvL

Gene amplifications cause high-level resistance against albicidin in gram-negative bacteria

Transcription activation by the resistance protein AlbA as a tool to evaluate derivatives of the antibiotic albicidin.

The occurrence of ansamers in the synthesis of cyclic peptides

Communication Breakdown: Dissecting the COM Interfaces between the Subunits of Nonribosomal Peptide Synthetases

Iodine-Mediated Tryptathionine Formation Facilitates the Synthesis of Amanitins

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity

The kalimantacin polyketide antibiotics inhibit fatty acid biosynthesis in Staphylococcus aureus by targeting the enoyl-acyl carrier protein binding site of FabI.

Collaborators (7)

Arnar Sigurdsson

Roderich D. Süssmuth

Bettina G. Keller

Alessandro Piai

Józef Lewandowski

Fereshteh Ghazisaeedi

Isabella Felli

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