Siobhán McClean

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Assoc Prof

University College Dublin College of Science

Ireland

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Siobhán McClean is an Associate Professor at University College Dublin, College of Science, Ireland. Her research focuses on the pathogenic mechanisms and immune responses related to cystic fibrosis, including studies on Aspergillus fumigatus, Burkholderia cenocepacia, and Moraxella catarrhalis. She is also involved in vaccine development initiatives and the characterization of virulence factors in various bacterial pathogens.

Recent Grants

Grant: Close

EncOVac - Encapsulated Oral Vaccine Technologies

Open Date: 2023-06-01

Close Date: 2026-05-01

Grant: Close

AIVRT - All Island Vaccine Research and Training Alliance

Open Date: 2022-09-01

Close Date: 2026-08-01

Grant: Close

AdaptaLOx - Adaptation of bacteria to low oxygen environment in chronic lung disease: Target for single treatment modality.

Open Date: 2021-12-01

Close Date: 2025-12-01

Grant: Close

BactiVax - anti-Bacterial Innovative Vaccines

Open Date: 2019-10-01

Close Date: 2024-09-01

Grant: Close

DiSarM: Development of a subunit vaccine against melioidosis

Open Date: 2018-02-01

Close Date: 2021-08-01

Articles (10)

Aspergillus fumigatus Supernatants Disrupt Bronchial Epithelial Monolayers: Potential Role for Enhanced Invasion in Cystic Fibrosis

Article Link

Year:

2023

The Direct Anti-Virulence but Not Bactericidal Activity of Human Neutrophil Elastase against Moraxella catarrhalis

Article Link

Year:

2023

A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis

Article Link

Year:

2023

GlnH, a Novel Antigen That Offers Partial Protection against Verocytotoxigenic Escherichia coli Infection

Article Link

Year:

2023

Protein with negative surface charge distribution, Bnr1, shows characteristics of a DNA-mimic protein and may be involved in the adaptation of Burkholderia cenocepacia

Article Link

Year:

2022

Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation

Article Link

Year:

2021

BpOmpW Antigen Stimulates the Necessary Protective T-Cell Responses Against Melioidosis

Article Link

Year:

2021

Mapping Global Prevalence of Acinetobacter baumannii and Recent Vaccine Development to Tackle It

Article Link

Year:

2021

A chronic strain of the cystic fibrosis pathogen Pandoraea pulmonicola expresses a heterogenous hypo-acylated lipid A

Article Link

Year:

2021

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

Article Link

Year:

2021

Collaborators (16)

Sveinbjorn Gizurarson

ICELAND

Justyna Roszkowiak

Professor assistant

University of Wrocław

POLAND

Aneesh Thakur

University of Copenhagen

DENMARK

Margaritha Mysior

Assistant Professor/Lecturer

University College Dublin

IRELAND

Žiga Jakopin

SLOVENIA

Antonio Molinaro

University of Naples Federico II

ITALY

Thomas R. Rogers

Trinity College Dublin

IRELAND

Mahavir Singh Dr

Director/Prof.

GERMANY

Carmen Alvarez-Dominguez

Profesor Contratado Doctor, Coordinador de área de Procesos Sanitarios and Director de TFM del Master Universitario de Gestión y Dirección Sanitaria

Universidad Internacional de La Rioja

SPAIN

Flaviana Di Lorenzo

ITALY

Daria Augustyniak

Wroclaw University of Science and Technology

POLAND

Alla Zamyatina

Assoc. Professor

University of Natural Resources and Life Sciences

AUSTRIA

Jeremy Simpson

Full Professor of Cell Biology

Dublin City University

IRELAND

Julie Renwick

Assistant Professor

Trinity College Dublin

IRELAND

MOLLY DOROTHY PITHER

University of Naples Federico II

ITALY

Sean Doyle

Professor

National University of Ireland, Maynooth

IRELAND

Siobhán McClean

Research Interests

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About

Recent Grants

Articles (10)

Aspergillus fumigatus Supernatants Disrupt Bronchial Epithelial Monolayers: Potential Role for Enhanced Invasion in Cystic Fibrosis

The Direct Anti-Virulence but Not Bactericidal Activity of Human Neutrophil Elastase against Moraxella catarrhalis

A universal stress protein upregulated by hypoxia has a role in Burkholderia cenocepacia intramacrophage survival: Implications for chronic infection in cystic fibrosis

GlnH, a Novel Antigen That Offers Partial Protection against Verocytotoxigenic Escherichia coli Infection

Protein with negative surface charge distribution, Bnr1, shows characteristics of a DNA-mimic protein and may be involved in the adaptation of Burkholderia cenocepacia

Rational Vaccine Design in Times of Emerging Diseases: The Critical Choices of Immunological Correlates of Protection, Vaccine Antigen and Immunomodulation

BpOmpW Antigen Stimulates the Necessary Protective T-Cell Responses Against Melioidosis

Mapping Global Prevalence of Acinetobacter baumannii and Recent Vaccine Development to Tackle It

A chronic strain of the cystic fibrosis pathogen Pandoraea pulmonicola expresses a heterogenous hypo-acylated lipid A

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

Collaborators (16)

Sveinbjorn Gizurarson

Justyna Roszkowiak

Aneesh Thakur

Margaritha Mysior

Žiga Jakopin

Antonio Molinaro

Thomas R. Rogers

Mahavir Singh Dr

Carmen Alvarez-Dominguez

Flaviana Di Lorenzo

Daria Augustyniak

Alla Zamyatina

Jeremy Simpson

Julie Renwick

MOLLY DOROTHY PITHER

Sean Doyle

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