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Slava Ziegler

Group leader

Max Planck Institute of Molecular Physiology

Germany

Research Interests

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Articles (20)

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2026

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2023

Collaborators (8)

Brenda Schulman

Director

Max Planck Institute of Biochemistry

GERMANY

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Astrid Stefanie Kahnt

Junior Research Group Leader

Goethe University Frankfurt

GERMANY

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Biprajit Sarkar

Professor

University of Stuttgart

GERMANY

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Thorsten Berg

GERMANY

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Kristina Žumer

Project Group Leader

Max Planck Institute for Multidisciplinary Sciences

GERMANY

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Carsten Strohmann

Technische Universität Dortmund

GERMANY

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Annika Schmidt

Technische Universität Dortmund

GERMANY

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Kerstin Hiesinger

Goethe University Frankfurt

GERMANY

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Slava Ziegler

Research Interests

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Articles (20)

Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders

Monovalent pseudo-natural products supercharge degradation of IDO1 by its native E3 KLHDC3

Design, Synthesis, and Biological Evaluation of Pseudo‐Natural Products Inspired by Aryloctahydroindole Alkaloids

Targeting a Glutamic Acid in PDEδ with Fluoromethyl-Aryl Electrophiles Impairs K-Ras Signaling

Pseudo‐Natural Products Inspired by Aspidospermidine‐, Strychnos‐, and Koumine Monoterpene Indole Alkaloids Reveal Pyrimidine Biosynthesis Inhibitors

An Indole Dearomatization Strategy for the Synthesis of Pseudo‐Natural Products

Identification of Natural Killer Cell Enhancers Through Mimicking of the Tumor Microenvironment

Adverse pro-tumorigenic effects of IDO1 catalytic inhibitors mediated by the non-enzymatic function of IDO1 in tumor cells

Phenotypic drug discovery

Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator

The Pseudo-Natural Product Tafbromin Selectively Targets the TAF1 Bromodomain 2

Detection of a Mitochondrial Fragmentation and Integrated Stress Response Using the Cell Painting Assay

Illuminating Dark Chemical Matter Using the Cell Painting Assay

Discovery of a Novel Pseudo‐Natural Product Aurora Kinase Inhibitor Chemotype through Morphological Profiling

A divergent intermediate strategy yields biologically diverse pseudo-natural products

Morphological Profiling Identifies the Motor Protein Eg5 as Cellular Target of Spirooxindoles

Cooperative Lewis Acid-1,2,3-Triazolium-Aryloxide Catalysis: Pyrazolone Addition to Nitroolefins as Entry to Diaminoamides

Inducin Triggers LC3‐Lipidation and ESCRT‐Mediated Lysosomal Membrane Repair

Synthetic Matching of Complex Monoterpene Indole Alkaloid Chemical Space

Morphological subprofile analysis for bioactivity annotation of small molecules

Collaborators (8)

Brenda Schulman

Astrid Stefanie Kahnt

Biprajit Sarkar

Thorsten Berg

Kristina Žumer

Carsten Strohmann

Annika Schmidt

Kerstin Hiesinger

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