Sreedharan Sajikumar

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Associate Professor

National University of Singapore (NUS)

Singapore

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Dr. Sreedharan Sajikumar is an Associate Professor at the National University of Singapore. His research focuses on synaptic plasticity, memory encoding, and the effects of stress on hippocampal function, as evidenced by his recent articles examining mechanisms of long-term potentiation and synaptic tagging in hippocampal areas. His work contributes to a deeper understanding of brain health and adaptability in response to various stressors.

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Metaplasticity of synaptic tagging and capture and its implications for maintaining long-term memory in normal and diseased neural networks

Open Date: 2008-01-01

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Articles (17)

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2025

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2022

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2022

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2022

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2021

Collaborators (1)

Haiyan Liu

Associate Professor

National University of Singapore (NUS)

SINGAPORE

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Sreedharan Sajikumar

Research Interests

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About

Recent Grants

Articles (17)

Hippocampal CA2 to CA1: A metaplastic switch for memory encoding

D1/D5 receptor activation promotes long‐term potentiation and synaptic tagging/capture in hippocampal area CA2

Differential expression of long-term depression, and synaptic tagging and capture in mouse hippocampal area CA2 synapses

Beyond boundaries: extended temporal flexibility in synaptic tagging and capture

Variations of Aberrant Volume, Activity, and Network Connectivity of Hippocampus in Adolescent Male Rats Exposed to Juvenile Stress

Nogo‐A‐mediated constraints on activity‐dependent synaptic plasticity and associativity in rat hippocampal CA2 synapses

Synapses tagged, memories kept: synaptic tagging and capture hypothesis in brain health and disease

Aging inverts the effects of p75NTR‐modulated mTOR manipulation on hippocampal neuron synaptic plasticity in male mice

Tumor-mediated microbiota alteration impairs synaptic tagging/capture in the hippocampal CA1 area via IL-1β production

Alteration of hippocampal CA2 plasticity and social memory in adult rats impacted by juvenile stress

Distinct contributions of ventral CA1/amygdala co-activation to the induction and maintenance of synaptic plasticity

Loss of Ca V 1.3 RNA editing enhances mouse hippocampal plasticity, learning, and memory

Inhibitory Metaplasticity in Juvenile Stressed Rats Restores Associative Memory in Adulthood by Regulating Epigenetic Complex G9a/GLP

Serotonin facilitates late-associative plasticity via synaptic tagging/cross-tagging and capture at hippocampal CA2 synapses in male rats

Modulation of the Ubiquitin-Proteasome System Restores Plasticity in Hippocampal Pyramidal Neurons of the APP/PS1 Alzheimer’s Disease-Like Mice

Long‐term plasticity in the hippocampus: maintaining within and ‘tagging’ between synapses

Inhibition of lysine methyltransferase G9a/GLP reinstates long-term synaptic plasticity and synaptic tagging/capture by facilitating protein synthesis in the hippocampal CA1 area of APP/PS1 mouse model of Alzheimer’s disease

Collaborators (1)

Haiyan Liu

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