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Stefan Coassin

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Assistant Professor

Medical University of Innsbruck

Austria

Research Interests

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Professors in Austria Professors in Biostatistics Biostatistics professors in Austria

About

Stefan Coassin is an Assistant Professor at Innsbruck Medical University in Austria. His research focuses on genetic variations influencing lipoprotein(a) and cardiovascular diseases, highlighted by recent work on mutation analysis using nanopore sequencing and the development of standardized measurement procedures for serum apolipoprotein(a). He has also contributed to understanding the genetic architecture of HDL-mediated cholesterol efflux and the role of Toll-Like Receptor 3 in aortic stenosis.

Recent Grants

Grant: Open

Multi-ancestry LPA KIV-2 haplotype analysis and imputation

Open Date: 2024-07-15

Close Date: 2028-01-14

Grant: Close

Genetics of LPA 4925G>A mutation

Open Date: 2018-01-01

Close Date: 2022-01-01

Grant: Close

Sequencing in LPA

Open Date: 2018-01-01

Close Date: 2020-01-01

Grant: Close

Development of a ultra-deep sequencing approach for the analysis of the Lipoprotein(a) KIV-2 repeat

Open Date: 2015-01-01

Close Date: 2017-01-01

Grant: Close

Application of Third Generation Sequencing to the genotyping of the Lipoprotein(a) KIV-2 repeat

Open Date: 2015-01-01

Close Date: 2017-01-01

Articles (14)

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2026

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2026

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (13)

Sebastian Schoenherr

Professor of Digital and Computational Genomics

Medical University of Innsbruck

AUSTRIA

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Florian Kronenberg

Director of the Institute

Medical University of Innsbruck

AUSTRIA

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Johan Björkegren

Associate Professor

Karolinska Institutet

SWEDEN

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Stefan Coassin

Research Interests

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About

Recent Grants

Articles (14)

LPA Kringle IV Type‐2 Genetic Variants Are Associated With Apolipoprotein (a) Size, Hypertension, and Nonfasting Glucose Levels

Umi-pipeline-nf: a modular and scalable workflow for UMI-tagged nanopore amplicon analysis with real-time sequencing integration and GPU-acceleration

Imputation Server PGS: an automated approach to calculate polygenic risk scores on imputation servers

Nanopore sequencing with unique molecular identifiers enables accurate mutation analysis and haplotyping in the complex lipoprotein(a) KIV-2 VNTR

Toll-Like Receptor 3 Mediates Aortic Stenosis Through a Conserved Mechanism of Calcification.

Commutability Assessment of Candidate Reference Materials for Lipoprotein(a) by Comparison of a MS-based Candidate Reference Measurement Procedure with Immunoassays

Development of an LC-MRM-MS-Based Candidate Reference Measurement Procedure for Standardization of Serum Apolipoprotein (a) Tests

KLKB1 and CLSTN2 are associated with HDL-mediated cholesterol efflux capacity in a genome-wide association study

Cis-epistasis at the LPA locus and risk of cardiovascular diseases

The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat.

Lipoprotein(a) beyond the kringle IV repeat polymorphism: The complexity of genetic variation in the LPA gene

The effect of LPA Thr3888Pro on lipoprotein(a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G>A.

Genome-Wide Characterization of a Highly Penetrant Form of Hyperlipoprotein(a)emia Associated With Genetically Elevated Cardiovascular Risk

Frequent LPA KIV-2 Variants Lower Lipoprotein(a) Concentrations and Protect Against Coronary Artery Disease.

Collaborators (13)

Sebastian Schoenherr

L. Renee Ruhaak

Lukas Forer

Leo Pölzl

Jonathon LeFaive

Dirk Meyer

Gissette Reyes-Soffer

Christa M. Cobbaert

Hubert Hackl

Albert Vernon Smith

Claudia Lamina

Florian Kronenberg

Johan Björkegren

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