Stefano Comai

Assistant Professor of Pharmacology (Tenure Track)

University of Padua

Italy

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Dr. Stefano Comai is an Assistant Professor of Pharmacology (Tenure Track) at the University of Padua, Italy. His research focuses on the interplay between neurochemistry and psychiatric conditions, specifically exploring the kynurenine pathway, its implications in mood disorders and schizophrenia, and innovative treatment strategies in psychiatry. He has published several articles examining the genetic landscape of neurovascular pathology, the effects of microdosing psychedelics, and the relationship between metabolic syndrome and mental health.

Articles (19)

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2025

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2025

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2023

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2022

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2021

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2021

Collaborators (9)

Michele Morari

University of Ferrara

ITALY

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Federico Suprani

ITALY

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Mirko Manchia

University of Cagliari

ITALY

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Lena Brundin

Professor

Van Andel Institute

UNITED STATES

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Gian Giacomo Consalez

Professor of Human Anatomy

Università Vita Salute San Raffaele

ITALY

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Claudia Pisanu

Assistant Professor (tenure track)

University of Cagliari

ITALY

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Gilles Guillemin

Professor of Neuroscience

Macquarie University

AUSTRALIA

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ANDREA MATTAREI

Associate Professor

Università degli Studi della Campania Luigi Vanvitelli Scuola di Medicina e Chirurgia

ITALY

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Jenny Sassone

Vita-Salute San Raffaele University

ITALY

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Stefano Comai

Research Interests

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About

Articles (19)

The Genetic Landscape of Kynurenine Predicts Neurovascular Pathology and Disrupted White Matter Integrity in Patients With Mood Disorders

Microdosing Psychedelics to Restore Synaptic Density in Schizophrenia

Moving toward precision and personalized treatment strategies in psychiatry

Neuropathic pain impairs sleep architecture, non-rapid eye movement sleep, and reticular thalamic neuronal activity

Metabolic Syndrome and Schizophrenia: Adding a Piece to the Interplay Between the Kynurenine Pathway and Inflammation

Preoperative Peripheral Blood Serotonin and Kynurenine Levels Are Associated With Oncological Outcomes in Glioblastoma IDH-wt Patients

Letter to the Editor regarding ‘Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone’

N-methyl-D-aspartate Receptors and Depression: Linking Psychopharmacology, Pathology and Physiology in a Unifying Hypothesis for the Epigenetic Code of Neural Plasticity

Melatonin, Melatonin Receptors and Sleep: Moving Beyond Traditional Views

Importance of the dysregulation of the kynurenine pathway on cognition in schizophrenia

Biological Factors Underpinning Suicidal Behaviour: An Update

Age-Related Effects of Exogenous Melatonin on Anxiety-like Behavior in C57/B6J Mice

Probing the Association between Cognition, Suicidal Behavior and Tryptophan Metabolism in a Sample of Individuals Living with Bipolar Disorder: A Secondary Analysis

Investigation of Genetic Variants Associated with Tryptophan Metabolite Levels via Serotonin and Kynurenine Pathways in Patients with Bipolar Disorder

Sex Differences in Responses to Antidepressant Augmentations in Treatment-Resistant Depression

Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline

Selective association of cytokine levels and kynurenine/tryptophan ratio with alterations in white matter microstructure in bipolar but not in unipolar depression

Tryptophan Metabolites, Cytokines, and Fatty Acid Binding Protein 2 in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Early Dysfunction of Substantia Nigra Dopamine Neurons in the ParkinQ311X Mouse

Collaborators (9)

Michele Morari

Federico Suprani

Mirko Manchia

Lena Brundin

Gian Giacomo Consalez

Claudia Pisanu

Gilles Guillemin

ANDREA MATTAREI

Jenny Sassone

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