Stephan Grupp

Section Chief, Cellular Therapy and Transplant

Children's Hospital of Philadelphia

United States

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About

Stephan Grupp serves as the Section Chief of Cellular Therapy and Transplant at the Children's Hospital of Philadelphia, USA. His research focuses on innovative therapies for hematologic malignancies, particularly in the areas of chimeric antigen receptor (CAR) cells, gene-modified T cell therapies, and acute graft-versus-host disease. Within his recent articles, he has explored CAR T cell therapy outcomes, gene transgene levels, and the safety of novel treatment modalities in pediatric populations.

Articles (14)

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2025

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2023

Collaborators (10)

Paibel Aguayo-HIraldo

Assistant Professor /Clinical director Transplant and Cellular Therapy

University of Southern California

UNITED STATES

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Stephan Kadauke

University of Pennsylvania

UNITED STATES

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Elizabeth Hexner

UNITED STATES

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Michael A. Pulsipher

UNITED STATES

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Hamideh Parhiz

University of Pennsylvania

UNITED STATES

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Liora Schultz

Clinical Assistant Professor

Stanford University

UNITED STATES

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Luis Gil-de-Gómez

Universidad de Cantabria

SPAIN

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Gregor Reid

Associate Professor

The University of British Columbia

CANADA

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James Riley

Professor

University of Pennsylvania

UNITED STATES

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Adam Cohen

Associate Professor, Clinician-Educator

University of Pennsylvania

UNITED STATES

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Stephan Grupp

Research Interests

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Articles (14)

Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies

Evaluation of in vivo CAR transgene levels in tisagenlecleucel-treated patients with relapsed/refractory B-ALL and DLBCL

Allogeneic chimeric antigen receptor cell therapies for cancer: progress made and remaining roadblocks

CD4+ T Cells Mediate Dendritic Cell Licensing to Promote Multi‐Antigen Anti‐Leukemic Immune Response

Novel MAGIC composite scores using both clinical symptoms and biomarkers best predict treatment outcomes of acute GVHD

INSPIRED Symposium Part 5: Expanding the Use of CAR T Cells in Children and Young Adults

ACT To Sustain: Adoptive Cell Therapy To Sustain Access to Non-Commercialized Genetically Modified Cell Therapies

Flares of acute graft-versus-host disease: a Mount Sinai Acute GVHD International Consortium analysis

Unanswered questions following reports of secondary malignancies after CAR-T cell therapy

INSPIRED Symposium Part 1: Clinical Variables Associated with Improved Outcomes for Children and Young Adults treated with Chimeric Antigen Receptor T cells for B cell Acute Lymphoblastic Leukemia

In vivo hematopoietic stem cell modification by mRNA delivery

Automation of Hematopoietic Cell Transplantation Outcomes Reporting Leads to Dramatic Reduction in Errors Reported to Real-World Data Registry

Prevention of veno-occlusive disease/sinusoidal obstruction syndrome: a never-ending story and no easy answer

Reply to W.H. Tong et al

Collaborators (10)

Paibel Aguayo-HIraldo

Stephan Kadauke

Elizabeth Hexner

Michael A. Pulsipher

Hamideh Parhiz

Liora Schultz

Luis Gil-de-Gómez

Gregor Reid

James Riley

Adam Cohen

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