Stephan Pless

Københavns Universitet

Denmark

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Articles (16)

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2025

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2024

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2024

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2024

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2024

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2022

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2022

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2021

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2021

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2021

Collaborators (12)

Iacopo Galleano

Københavns Universitet

DENMARK

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Mike Althaus

Professor in Biology (Physiology and Neurobiology)

Bonn-Rhein-Sieg University of Applied Sciences

GERMANY

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Estelle Toulme

GERMANY

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Vincenzo Carnevale

Research Professor

Temple University

UNITED STATES

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Han Chow Chua

Lecturer

University of Sydney

AUSTRALIA

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Andrea Sinz

GERMANY

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Ganga Deshar

Københavns Universitet

DENMARK

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Mette Homann Poulsen

Københavns Universitet

DENMARK

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Nina Braun

Københavns Universitet

DENMARK

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Timothy Lynagh

University of Bergen

NORWAY

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Zeshan Pervez Sheikh

Københavns Universitet

DENMARK

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Keith Khoo

Københavns Universitet

DENMARK

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Stephan Pless

Research Interests

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Articles (16)

The sodium leak channel NALCN is regulated by neuronal SNARE complex proteins

Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore region

Human P2X7 receptor variants Gly150Arg and Arg276His polymorphisms have differential effects on risk association and cellular functions in pancreatic cancer

Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channels

Dynamic conformational changes of acid-sensing ion channels in different desensitizing conditions

Unplugging lateral fenestrations of NALCN reveals a hidden drug binding site within the pore region

P2X2 receptor subunit interfaces are missense variant hotspots, where mutations tend to increase apparent ATP affinity

Conformational decoupling in acidsensing ion channels uncovers mechanism and stoichiometry of PcTx1mediated inhibition

Structural architecture of the human NALCN channelosome

Structure-guided unlocking of NaX reveals a non-selective tetrodotoxin-sensitive cation channel

The suitability of high throughput automated patch clamp for physiological applications

Functional cross-talk between phosphorylation and disease-causing mutations in the cardiac sodium channel Nav1.5

The M1 and pre-M1 segments contribute differently to ion selectivity in ASICs and ENaCs.

Acid-sensing ion channels as potential therapeutic targets

High-throughput characterization of photocrosslinker-bearing ion channel variants to map residues critical for function and pharmacology

The gating pore blocker 1-(2,4-xylyl)guanidinium selectively inhibits pacemaking of midbrain dopaminergic neurons

Collaborators (12)

Iacopo Galleano

Mike Althaus

Estelle Toulme

Vincenzo Carnevale

Han Chow Chua

Andrea Sinz

Ganga Deshar

Mette Homann Poulsen

Nina Braun

Timothy Lynagh

Zeshan Pervez Sheikh

Keith Khoo

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