Stephanie Georgina Dakin

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Associate Professor of Musculoskeletal Sciences

University of Oxford

United Kingdom

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About

Stephanie Georgina Dakin is an Associate Professor of Musculoskeletal Sciences at the University of Oxford, UK. Her research focuses on musculoskeletal diseases, with recent articles exploring topics such as transcriptomics for therapeutic targeting in soft tissue joint disease, chronic musculoskeletal pain in migrants, and cellular characterization of advanced osteoarthritis. She is also involved in investigating the role of the microbiome in rheumatoid arthritis and utilizing three-dimensional in-vitro approaches for modeling soft-tissue joint diseases.

Recent Grants

Grant: Close

Understanding frozen shoulder, A human disease model of resolving inflammatory fibrosis,

Open Date: 2022-01-01

Close Date: 2024-01-01

Grant: Close

Frozen shoulder: A human disease model of resolving inflammatory fibrosis.

Open Date: 2021-01-01

Close Date: 2024-01-01

Grant: Close

Resolving pathogenic cell types in human tendinopathy

Open Date: 2021-01-01

Close Date: 2024-01-01

Grant: Close

Elucidating T cell phenotype and function in frozen shoulder.

Open Date: 2020-01-01

Close Date: 2021-01-01

Grant: Close

Stromal cells as therapeutic targets in soft tissue disease of the joint

Open Date: 2019-12-01

Close Date: 2024-11-01

Articles (18)

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2022

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2022

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2021

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (9)

Andy Zeng

University of Toronto

CANADA

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Roberta Blake

Writtle University College

UNITED KINGDOM

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Sarah Snelling

University of Oxford

UNITED KINGDOM

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Jonathan Rees

University of Oxford

UNITED KINGDOM

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James Charlesworth

University of Oxford

UNITED KINGDOM

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Pierre-Alexis Mouthuy

Associate Professor

University of Oxford

UNITED KINGDOM

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Lucy MacDonald

University of Glasgow

UNITED KINGDOM

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Moustafa Attar

University of Oxford

UNITED KINGDOM

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David Keene

University of Oxford

UNITED KINGDOM

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Stephanie Georgina Dakin

Research Interests

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About

Recent Grants

Articles (18)

A single cell atlas of frozen shoulder capsule identifies features associated with inflammatory fibrosis resolution

Leveraging cutting-edge transcriptomics to inform precision therapeutic targeting for soft tissue joint disease.

Selective advantage of mutant stem cells in human clonal hematopoiesis is associated with attenuated response to inflammation and aging.

Exploring the burden, prevalence and associated factors of chronic musculoskeletal pain in migrants from North Africa and Middle East living in Europe: a scoping review.

Cellular characterisation of advanced osteoarthritis knee synovium.

Three-dimensional, in-vitro approaches for modelling soft-tissue joint diseases.

The role of the microbiome in rheumatoid arthritis: a review.

Osteoarthritis: a narrative review of molecular approaches to disease management.

Impact of age on unicompartmental knee arthroplasty outcomes: a systematic review and meta-analysis.

Single cell multi-omics characterise discrete human tendon cells populations that persist in vitro and on fibrous scaffolds.

Editorial: Tendinopathy Research- How Cutting Edge Developments Inform the Future Therapeutic Landscape.

Interleukin-17 Cytokines and Receptors: Potential Amplifiers of Tendon Inflammation.

Comparison of Cellular Responses to TGF-β1 and BMP-2 Between Healthy and Torn Tendons.

Interleukin-17A Causes Osteoarthritis-Like Transcriptional Changes in Human Osteoarthritis-Derived Chondrocytes and Synovial Fibroblasts <i>In Vitro</i>.

Electrospun Scaffold Micro-Architecture Induces an Activated Transcriptional Phenotype within Tendon Fibroblasts.

Multi-omic single cell analysis resolves novel stromal cell populations in healthy and diseased human tendon.

Rotator cuff repair with biological graft augmentation causes adverse tissue outcomes.

Histological evaluation of cellular response to a multifilament electrospun suture for tendon repair.

Collaborators (9)

Andy Zeng

Roberta Blake

Sarah Snelling

Jonathan Rees

James Charlesworth

Pierre-Alexis Mouthuy

Lucy MacDonald

Moustafa Attar

David Keene

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