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Stephen Brohawn

Assistant Professor

University of California, Berkeley

United States

Research Interests

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About

Stephen Brohawn is an Assistant Professor at the University of California, Berkeley, USA. His research focuses on optogenetics, mechanosensitive ion channels, and structural biology, as evidenced by his recent articles on channelrhodopsins, mechanosensitive K+ channels, and the SARS-CoV-2 M protein. Additionally, he investigates the structural basis for protein interactions and lipid-mediated gating mechanisms.

Articles (21)

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Collaborators (5)

Uday Jagadisan

University of Pittsburgh

UNITED STATES

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Jennifer A. Doudna

University of California

UNITED STATES

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Em Ben. SORUM

Assistant Professor

Cooper Medical School of Rowan University

UNITED STATES

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Naomi Latorraca

Assistant Professor

Columbia University Irving Medical Center

UNITED STATES

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Isabel Esain-Garcia

Lecturer

University of California, Berkeley

UNITED STATES

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Stephen Brohawn

Research Interests

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About

Articles (21)

Mechanisms of intracellular pH gating and local anesthetic inhibition of the two-pore domain K + channel TASK-2

A Noncontiguous Code for RNA-Guided DNA Recognition at the Origin of CRISPR-Cas

VIPR RNA-guided DNA recognition by noncontiguous geometric triplex formation

Meet the author: Stephen Brohawn

Structural basis for proton inhibition of the two-pore domain K+ channel TASK-1

Optogenetic restoration of high-sensitivity vision using ChRmine- and ChroME-based channelrhodopsins

Assembly and lipid-gating of LRRC8A:D volume-regulated anion channels

Coupling sensor to enzyme in the voltage sensing phosphatase

Tension activation of mechanosensitive two-pore domain K+ channels TRAAK, TREK-1, and TREK-2

Structural basis for assembly and lipid-mediated gating of LRRC8A:C volume-regulated anion channels

Structure of SARS-CoV-2 M protein in lipid nanodiscs

Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A

Structure of SARS-CoV-2 M protein in lipid nanodiscs

Cryo-EM structures of the channelrhodopsin ChRmine in lipid nanodiscs

Structural Basis for pH-gating of the K+ channel TWIK1 at the selectivity filter

High-performance microbial opsins for spatially and temporally precise perturbations of large neuronal networks

Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A

Structure of SARS-CoV-2 M protein in lipid nanodiscs

Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca2+-dependent switch from intra- to intermembrane dimerization

Physical basis for distinct basal and mechanically gated activity of the human K+ channel TRAAK

Author Correction: Cryo-EM structure of SARS-CoV-2 ORF3a in lipid nanodiscs

Collaborators (5)

Uday Jagadisan

Jennifer A. Doudna

Em Ben. SORUM

Naomi Latorraca

Isabel Esain-Garcia

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