Stephen Chong

Harvard University

United States

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Articles (10)

Year:

2025

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2025

Year:

2025

Year:

2024

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2023

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2021

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2021

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2021

Year:

2021

Year:

2021

Collaborators (3)

Li Ren Kong

Assistant Professor of Cancer and Stem Cell Biology

Nanyang Technological University

SINGAPORE

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Shazib Pervaiz

Professor

National University of Singapore (NUS)

SINGAPORE

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Chantal Guillemette

Professor

Laval University

CANADA

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Stephen Chong

Research Interests

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Articles (10)

BCL-2 dependence is a favorable predictive marker of response to therapy for chronic lymphocytic leukemia

Superoxide-mediated phosphorylation and stabilization of Mcl-1 by AKT underlie venetoclax resistance in hematologic malignancies

Large-scale dependency and drug screens to characterize the therapeutic vulnerabilities of multiple myeloma with 1q+

Hypomethylating agent decitabine sensitizes diffuse large B-cell lymphoma to venetoclax.

Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies.

Rationale for the combination of venetoclax and ibrutinib in T-prolymphocytic leukemia.

The redox-senescence axis and its therapeutic targeting

Sustained IKKβ phosphorylation and NF-κB activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56γ3 and PP2A inactivation

BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia.

PIK3CB is involved in metastasis through the regulation of cell adhesion to collagen I in pancreatic cancer.

Collaborators (3)

Li Ren Kong

Shazib Pervaiz

Chantal Guillemette

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