Stephen Walker

Associate Professor

Stony Brook University

United States

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About

Stephen Walker is an Associate Professor at Stony Brook University, USA. His research encompasses areas such as antimicrobial efficacy, drug-target interactions, and the therapeutic implications of oral diseases. Recent articles highlight his work on leucyl-tRNA-synthetase inhibition, novel therapeutic approaches for diabetes and periodontal disease, and the evaluation of materials for dental applications.

Articles (13)

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2025

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2025

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2025

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2020

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2020

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2020

Collaborators (4)

Peter Tonge

Professor

Stony Brook University

UNITED STATES

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Jarrod French

University of Minnesota

UNITED STATES

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Kylie Langlois

Southern California Coastal Water Research Project

UNITED STATES

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John Haley

Associate Professor

Stony Brook University

UNITED STATES

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Stephen Walker

Research Interests

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Articles (13)

Time-Dependent Inhibition of Leucyl-tRNA-Synthetase (LeuRS): Insight into Target Vulnerability

Diabetes, periodontal disease, and novel therapeutic approaches- host modulation therapy.

Effect of a chemically-modified-curcumin on dental resin biodegradation.

Non-cytotoxic Root Canal Dressing with Improved Antimicrobial Efficacy

Efficacy of hypochlorous acid (HOCl) fog in sanitizing surfaces against Enterococcus faecalis

Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity

Structure-Kinetic Relationship Studies for the Development of Long Residence Time LpxC Inhibitors

Impact of Target Turnover on the Translation of Drug-Target Residence Time to Time-Dependent Antibacterial Activity

Evaluation of different materials used for sealing of implant abutment access channel and the peri-implant sulcus microbiota: A 6-month, randomized controlled trial

The impact of TiO<sub>2</sub> nanoparticle exposure on transmembrane cholesterol transport and enhanced bacterial infectivity in HeLa cells

Structural Basis for the Regulation of Biofilm Formation and Iron Uptake in A. baumannii by the Blue-Light-Using Photoreceptor, BlsA

Correlating Drug-Target Residence Time and Post-antibiotic Effect: Insight into Target Vulnerability

Positron Emission Tomography Imaging of Staphylococcus aureus Infection Using a Nitro-Prodrug Analogue of 2-[<sup>18</sup>F]F- p-Aminobenzoic Acid

Collaborators (4)

Peter Tonge

Jarrod French

Kylie Langlois

John Haley

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