Steven Mansoor

Assistant Professor of Medicine

Oregon Health & Science University

United States

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Dr. Steven Mansoor is an Assistant Professor of Medicine at Oregon Health & Science University in the United States. His research focuses on the structural and functional characteristics of purinergic receptors, particularly in relation to hearing loss and allosteric modulation. His recent articles explore the architecture of various P2X receptors and their implications for pharmacology and receptor gating mechanisms.

Articles (5)

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Collaborators (2)

Parthiban Marimuthu

Åbo Akademi University

FINLAND

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Michael Godsey

Associate Professor

Larner College of Medicine, University of Vermont

UNITED STATES

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Steven Mansoor

Research Interests

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Articles (5)

Subtype-specific structural features of the hearing loss–associated human P2X2 receptor

Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket

High-affinity agonism at the P2X7 receptor is mediated by three residues outside the orthosteric pocket

P2X 7 receptors exhibit at least three modes of allosteric antagonism

Cryo-EM structures of the human P2X1 receptor reveal subtype-specific architecture and antagonism by supramolecular ligand-binding

Collaborators (2)

Parthiban Marimuthu

Michael Godsey

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