Sven Falke

Deutsches Elektronen-Synchrotron DESY

Germany

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Articles (20)

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2025

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2025

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2024

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2024

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2024

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2022

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2022

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2022

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2021

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2021

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2021

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2021

Collaborators (4)

Christian Betzel

Prof.

Universität Hamburg

GERMANY

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Hideaki Tsuge

Professor

Kyoto University

JAPAN

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Arwen R. Pearson

Universität Hamburg

GERMANY

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Christopher Radka

Assistant Professor

University of Kentucky

UNITED STATES

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Sven Falke

Research Interests

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Articles (20)

Drug repurposing: Identification and X-ray crystallographic analyses of US-FDA approved drugs against carbonic anhydrase-II.

Unraveling binding interactions between methasterone and bovine serum albumin (BSA): A spectroscopic and computational study.

Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds.

Molecular insights into the dynamic modulation of bacterial ClpP function and oligomerization by peptidomimetic boronate compounds

Identification, crystallization, and first X-ray structure analyses of phenyl boronic acid-based inhibitors of human carbonic anhydrase-II

Identification, crystallization, and first X-ray structure analyses of phenyl boronic acid-based inhibitors of human carbonic anhydrase-II.

SARS-CoV-2 M<SUP>pro</SUP> responds to oxidation by forming disulfide and NOS/SONOS bonds

SARS-CoV-2 M<sup>pro</sup> responds to oxidation by forming disulfide and NOS/SONOS bonds.

Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors

Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors

Intrinsically disordered plant protein PARCL colocalizes with RNA in phase-separated condensates whose formation can be regulated by mutating the PLD

Structural characterization and antibacterial activity of silver nanoparticles synthesized using a low-molecular-weight Royal Jelly extract

Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease.

Crystal structure of an extracellular superoxide dismutase from Onchocerca volvulus and implications for parasite-specific drug development

Hydrazones and Thiosemicarbazones Targeting Protein-Protein-Interactions of SARS-CoV-2 Papain-like Protease.

Tracing transport of protein aggregates in microgravity versus unit gravity crystallization

Eruca sativa seed napin structural insights and thorough functional characterization.

Characterization of Conjugates between α-Lactalbumin and Benzyl Isothiocyanate—Effects on Molecular Structure and Proteolytic Stability

Structural Features of a Full-Length Ubiquitin Ligase Responsible for the Formation of Patches at the Plasma Membrane

Structure of SARS-CoV-2 papain-like protease PLpro reveals a framework for antiviral inhibitor design

Collaborators (4)

Christian Betzel

Hideaki Tsuge

Arwen R. Pearson

Christopher Radka

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