Tadayoshi Karasawa

Assistant Professor

Jichi Medical University

Japan

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About

Dr. Tadayoshi Karasawa is an Assistant Professor at Jichi Medical University in Japan. His research areas include kidney inflammation, ferroptosis, and the mechanisms of NLRP3 inflammasome activation. Recent publications highlight his work on the roles of gasdermin D and S100A9 in inflammation, as well as the effects of various inhibitors on cellular processes involved in diseases such as atherosclerosis and acute kidney injury.

Articles (14)

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2025

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2024

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2024

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2022

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2022

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2022

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2021

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2020

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2020

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2020

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2020

Collaborators (5)

Masafumi Takahashi

Professor

Jichi Medical University

JAPAN

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Chong Yang

National University of Singapore

SINGAPORE

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Hiroaki Kimura

Professor

Fukuoka International University of Health and Welfare

JAPAN

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Sachiko Watanabe

Kyoto University

JAPAN

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Hironori Takahashi

Professor

Jichi Medical University

JAPAN

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Tadayoshi Karasawa

Research Interests

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Articles (14)

Low Potassium Triggers Tubular Epithelial NLR Family Pyrin Domain-Containing 3/Apoptosis-Associated Speck-Like Protein-Containing CARD–Driven Kidney Inflammation Independently of Inflammasomes

Gasdermin D regulates soluble fms-like tyrosine kinase 1 release in macrophages

Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis

Caspase-11 deficiency attenuates neutrophil recruitment into the atherosclerotic lesion in apolipoprotein E-deficient mice

dsDNA-induced AIM2 pyroptosis halts aberrant inflammation during rhabdomyolysis-induced acute kidney injury

A Myb enhancer-guided analysis of basophil and mast cell differentiation

Cryo-sensitive aggregation triggers NLRP3 inflammasome assembly in cryopyrin-associated periodic syndrome

Calciprotein Particles Induce IL-1β/α-Mediated Inflammation through NLRP3 Inflammasome-Dependent and -Independent Mechanisms

Elevated S100A9 in preeclampsia induces soluble endoglin and IL-1β secretion and hypertension via the NLRP3 inflammasome

β-hydroxybutyrate suppresses NLRP3 inflammasome-mediated placental inflammation and lipopolysaccharide-induced fetal absorption

ASC regulates platelet activation and contributes to thrombus formation independent of NLRP3 inflammasome

Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells

Crucial role of NLRP3 inflammasome in a murine model of Kawasaki disease

Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure

Collaborators (5)

Masafumi Takahashi

Chong Yang

Hiroaki Kimura

Sachiko Watanabe

Hironori Takahashi

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