Taichi Isobe

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Kyushu University

Japan

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Recent Grants

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Characterization of immune responses in tumor microenvironment of patients with clonal hematopoiesis

Open Date: 2021-04-01

Close Date: 2024-03-31

Grant: Close

Establishment of a new model for human colorectal cancers

Open Date: 2019-04-01

Close Date: 2021-03-31

Grant: Close

Molecular basis for the establishment of early metastatic lesion through cell adaptation

Open Date: 2015-04-01

Close Date: 2017-03-31

Articles (19)

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UNITED STATES

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Kenji Tsuchihashi

Assistant Professor

Kyushu University

JAPAN

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Junko Mukohyama

Lecturer

International University of Health and Welfare Mita Hospital

JAPAN

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Assistant Professor

Columbia University Irving Medical Center

UNITED STATES

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Piero Dalerba

Columbia University Irving Medical Center

UNITED STATES

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Qingyun Li

Assistant Professor

Washington University School of Medicine

UNITED STATES

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Antoine de Morrée

Tenure-track Assistant Professor

Aarhus University

DENMARK

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Taichi Isobe

Research Interests

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Recent Grants

Articles (19)

Development of iPSC-derived T cells targeting EGFR neoantigens in non-small cell lung cancer

Metastatic urachal carcinoma treated with trifluridine/tipiracil and bevacizumab: a case report

Efficacy of pembrolizumab in microsatellite-stable, tumor mutational burden-high metastatic colorectal cancer: genomic signatures and clinical outcomes

A molecular cell atlas of mouse lemur, an emerging model primate.

Mouse lemur cell atlas informs primate genes, physiology and disease.

Spatial dynamics of CD39&lt;sup&gt;+&lt;/sup&gt;CD8&lt;sup&gt;+&lt;/sup&gt; exhausted T cell reveal tertiary lymphoid structures-mediated response to PD-1 blockade in esophageal cancer.

Impact of Genomic Alterations on Efficacy of Trastuzumab Deruxtecan Against Human Epidermal Growth Factor Receptor-2–Positive Advanced Gastric Cancer

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome.

RHAMM marks proliferative subpopulation of human colorectal cancer stem cells.

Preferential B cell differentiation by combined immune checkpoint blockade for renal cell carcinoma is associated with clinical response and autoimmune reactions

Molecular hallmarks of heterochronic parabiosis at single-cell resolution

Upregulation of BMI1-suppressor miRNAs (miR-200c, miR-203) during terminal differentiation of colon epithelial cells.

Inhibition of insulin‐like growth factor‐1 receptor enhances eribulin‐induced DNA damage in colorectal cancer

Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions.

Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets

IMPROVE bleeding score predicts major bleeding in advanced gastrointestinal cancer patients with venous thromboembolism

Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model

Does the Use of Peripheral Immune-Related Markers Indicate Whether to Administer Pazopanib, Trabectedin, or Eribulin to Advanced Soft Tissue Sarcoma Patients?

Predictive impact of C-reactive protein to albumin ratio for recurrent or metastatic head and neck squamous cell carcinoma receiving nivolumab

Collaborators (14)

Hirofumi Ohmura

Takahiro Maeda

Makoto Endo

Masao Maeda

Laura Amaya

Kenji Tsuchihashi

Junko Mukohyama

Eishi Baba

Makoto Nakagawa

Daisuke Kiyozawa

Vincenzo Gennarino

Piero Dalerba

Qingyun Li

Antoine de Morrée

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Spatial dynamics of CD39<sup>+</sup>CD8<sup>+</sup> exhausted T cell reveal tertiary lymphoid structures-mediated response to PD-1 blockade in esophageal cancer.