Taiho Kambe

准教授 / Associate Professor

Kyoto University

Japan

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Dr. Taiho Kambe is an Associate Professor at Kyoto University in Japan. His research primarily focuses on metal ion homeostasis, specifically the roles of zinc and manganese in cellular metabolism and enzyme activity. Recent publications have explored the implications of zinc deficiency on various biological processes, the mechanisms of manganese transport, and the role of ZNT proteins in glycosylation and sphingolipid metabolism.

Articles (15)

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2024

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2023

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2023

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2022

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2022

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JAPAN

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Seiichiro Himeno

Visiting Professor

Showa University

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Yuki Manabe

助教 / Assistant Professor

Kyoto University

JAPAN

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Katsutoshi Nishino

Tokyo Institute of Technology

JAPAN

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Yasuo Uchida

Tohoku University

JAPAN

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Hiroyuki Yasui

Professor

Kyoto Pharmaceutical University

JAPAN

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Nobukazu Shitan

Kobe Pharmaceutical University

JAPAN

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Taiho Kambe

Research Interests

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Articles (15)

ZNT5-6 and ZNT7 play an integral role in protein N-glycosylation by supplying Zn<sup>2+</sup> to Golgi α-mannosidase II.

Rate of hydrolysis of the phosphate esters of B vitamins is reduced by zinc deficiency: In vitro and in vivo

Reduced Mn uptake of pleiotropic ZIP8 SNP is caused by its loss of Mn-responsive accumulation on the cell-surface

Zinc and manganese homeostasis closely interact in mammalian cells

Pigmentation and TYRP1 expression are mediated by zinc through the early secretory pathway-resident ZNT proteins

Novel SLC30A2 mutations in the pathogenesis of transient neonatal zinc deficiency

Metalation and activation of Zn2+ enzymes via early secretory pathway-resident ZNT proteins

Effects of individual amino acid mutations of zinc transporter ZIP8 on manganese- and cadmium-transporting activity

Early secretory pathway-resident Zn transporter proteins contribute to cellular sphingolipid metabolism through activation of sphingomyelin phosphodiesterase 1

Methionine metabolism regulates pluripotent stem cell pluripotency and differentiation through zinc mobilization.

Zinc transport via ZNT5-6 and ZNT7 is critical for cell surface glycosylphosphatidylinositol-anchored protein expression

Manganese transport in mammals by zinc transporter family proteins, ZNT and ZIP

Enhancing effect of Panax ginseng on Zip4-mediated zinc influx into the cytosol

Loss-of-function SLC30A2 mutants are associated with gut dysbiosis and alterations in intestinal gene expression in preterm infants

Role of Vitamins and Minerals in Health and Diseases

Collaborators (11)

Daigo Sumi

Toshihiko Katoh

Masato Kinoshita

Soshiro Kashio

Takane Katayama

Seiichiro Himeno

Yuki Manabe

Katsutoshi Nishino

Yasuo Uchida

Hiroyuki Yasui

Nobukazu Shitan

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