Takanobu Shimizu

Project Assistant Professor

Tokai University School of Medicine

Japan

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Takanobu Shimizu is a Project Assistant Professor at the School of Medicine, Tokai University, Japan. His research focuses on the intersection of viral infection and inflammatory diseases, as well as the molecular mechanisms of tumor suppression and transcription regulation. Recent publications highlight his work on the therapeutic effects of entecavir in colitis and the role of RASSF6 in the regulation of p53-related pathways.

Articles (3)

Year:

2022

Year:

2021

Year:

2020

Collaborators (2)

Joaquim Carreras

University Lecturer

Tokai University School of Medicine

JAPAN

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Masatoshi Kakizaki

National Institute of Infectious Diseases

JAPAN

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Takanobu Shimizu

Research Interests

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Articles (3)

Anti-HBV drug entecavir ameliorates DSS-induced colitis through PD-L1 induction

DNA damage triggers the nuclear accumulation of RASSF6 tumor suppressor protein via CDK9 and BAF53 to regulate p53-target gene transcription.

The RAS-interacting chaperone UNC119 drives the RASSF6–MDM2–p53 axis and antagonizes RAS-mediated malignant transformation

Collaborators (2)

Joaquim Carreras

Masatoshi Kakizaki

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