Takehito Uruno

Associate Professor

Kyushu University

Japan

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About

Takehito Uruno is an Associate Professor at Kyushu University, Japan. His research focuses on immunology, particularly in the context of atopic dermatitis, antitumor immunity, and innate lymphoid cell function. Recent articles highlight his work on the DOCK8 gene and its implications in immunity and cancer biology.

Articles (7)

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Professor

Kyushu University

JAPAN

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Kazufumi Kunimura

Assistant Professor

Kyushu University

JAPAN

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Takehito Uruno

Research Interests

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Articles (7)

Identification of a functional DOCK8 gene polymorphism associated with atopic dermatitis

Pharmacological intervention of cholesterol sulfate-mediated T cell exclusion promotes antitumor immunity

Cancer-derived cholesterol sulfate is a key mediator to prevent tumor infiltration by effector T cells

DOCK8 deficiency causes a skewing to type 2 immunity in the gut with expansion of group 2 innate lymphoid cells

Targeted inhibition of EPAS1-driven IL-31 production by a small-molecule compound

A conserved PI(4,5)P2–binding domain is critical for immune regulatory function of DOCK8

DOCK8 controls survival of group 3 innate lymphoid cells in the gut through Cdc42 activation

Collaborators (8)

Takuto Ohki

Takaya Togo

Yuki Sugiura

Daisuke Takaya

Keisuke Matsubara

Takeshi Nakahara

Yoshinori Fukui

Kazufumi Kunimura

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