Takumi Ueda

Professor

Osaka University

Japan

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About

Takumi Ueda is a Professor at The University of Osaka, Japan. His research focuses on membrane permeability in cyclic peptides, chemigenetic indicators, and the activation mechanisms of G-protein-coupled receptors (GPCRs). Recent publications include studies on peptide-based molecular scaffolds, water permeation through nanochannels, and the dynamics of membrane proteins as revealed by NMR techniques.

Articles (10)

Year:

2023

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2020

Year:

2020

Collaborators (1)

Yoshimitsu Itoh

Associate Professor

University of Tokyo

JAPAN

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Takumi Ueda

Research Interests

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Articles (10)

Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptides

Chemigenetic indicators based on synthetic chelators and green fluorescent protein

Ultrafast water permeation through nanochannels with a densely fluorous interior surface

Activation mechanism of the μ-opioid receptor by an allosteric modulator

Function-related dynamics of GPCRs

Oligo(N-methylalanine) as a Peptide-Based Molecular Scaffold with a Minimal Structure and High Density of Functionalizable Sites

Biphasic activation of β-arrestin 1 upon interaction with a GPCR revealed by methyl-TROSY NMR

Function-Related Dynamics in Multi-Spanning Helical Membrane Proteins Revealed by Solution NMR

Activation of adenosine A<sub>2A</sub> receptor by lipids from docosahexaenoic acid revealed by NMR

Structural equilibrium underlying ligand-dependent activation of β<sub>2</sub>-adrenoreceptor

Collaborators (1)

Yoshimitsu Itoh

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