Taran Gujral

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Associate Professor

Fred Hutchinson Cancer Research Center

United States

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About

Dr. Taran Gujral is an Associate Professor at the Fred Hutchinson Cancer Center in the United States. His research focuses on cancer drug testing, the molecular mechanisms of fibrolamellar carcinoma, and innovative approaches for real-time monitoring of tumor responses. Recent articles highlight his work on live microtissue manipulation, immune-checkpoint therapy, and the therapeutic vulnerabilities in various cancer pathways.

Recent Grants

Grant: Close

Novel Therapeutics for Fibrolamellar Carcinoma

Open Date: 2017-10-01

Close Date: 2018-09-01

Grant: Close

Frizzled2 Signaling in Metastatic Cancers

Open Date: 2016-09-30

Close Date: 2019-08-31

Grant: Close

Developing a protein array based high-throughput method to dissect EGFR signalling pathway

Open Date: 2009-05-01

Close Date: 2012-04-30

Grant: Close

Identification and characterization of novel RET kinase inhibitor(s)

Open Date: 2007-05-01

Close Date: 2008-09-15

Grant: Close

American Association for Cancer Research - Los Angeles, CAThe RET receptor tyrosine kinase causes activation of the B-catenin pathway

Open Date: 2007-04-01

Close Date: 2007-05-01

Articles (16)

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2025

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2022

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2022

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2022

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2021

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2021

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2021

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2020

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2020

Collaborators (10)

Frank Szulzewsky

Assistant Professor

University of Utah Health Huntsman Cancer Institute

UNITED STATES

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Nao Nishida-Aoki

Assistant Professor

Waseda University

JAPAN

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Margaret. Juliana McElrath

Director, Professor and Senior Vice President

Fred Hutchinson Cancer Research Center

UNITED STATES

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Eleonora Dondossola

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Eric Holland

Fred Hutchinson Cancer Research Center

UNITED STATES

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Eva Corey

Professor

University of Washington

UNITED STATES

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P.J. Cimino

National Institutes of Health

UNITED STATES

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Michael Zager

Fred Hutchinson Cancer Research Center

UNITED STATES

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Felix Sahm

University Hospital Heidelberg

GERMANY

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Albert Folch

University of Washington

UNITED STATES

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Taran Gujral

Research Interests

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About

Recent Grants

Articles (16)

Low-Cost Robotic Manipulation of Live Microtissues for Cancer Drug Testing

DNAJ-PKAc fusion heightens PLK1 inhibitor sensitivity in fibrolamellar carcinoma

Label-free, real-time monitoring of cytochrome C drug responses in microdissected tumor biopsies with a multi-well aptasensor platform

A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities

A kinase to cytokine explorer to identify molecular regulators and potential therapeutic opportunities

Drug testing of monodisperse arrays of live microdissected tumors using a valved multiwell microfluidic platform

Both YAP1-MAML2 and constitutively active YAP1 drive the formation of tumors that resemble NF2 mutant meningiomas in mice

Olverembatinib inhibits SARS‐CoV‐2‐Omicron variant‐mediated cytokine release in human peripheral blood mononuclear cells

Deep neural network modeling identifies biomarkers of response to immune-checkpoint therapy

Proteomic and Transcriptomic Profiling Reveals Mitochondrial Oxidative Phosphorylation as Therapeutic Vulnerability in Androgen Receptor Pathway Active Prostate Tumors

Polypharmacologic Reprogramming of Tumor-Associated Macrophages toward an Inflammatory Phenotype

Computational modeling identifies multitargeted kinase inhibitors as effective therapies for metastatic, castration-resistant prostate cancer

Machine learning identifies molecular regulators and therapeutics for targeting SARS‐CoV2‐induced cytokine release

α-arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis.

Microdissected "cuboids" for microfluidic drug testing of intact tissues.

Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma.

Collaborators (10)

Frank Szulzewsky

Nao Nishida-Aoki

Margaret. Juliana McElrath

Eleonora Dondossola

Eric Holland

Eva Corey

P.J. Cimino

Michael Zager

Felix Sahm

Albert Folch

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