Terence Flotte

Dean, Provost and Executive Deputy Chancellor

University of Massachusetts Chan Medical School

United States

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About

Dr. Terence Flotte is the Dean, Provost, and Executive Deputy Chancellor at the University of Massachusetts Chan Medical School in the United States. His research primarily focuses on gene therapy, particularly in the context of alpha-1 antitrypsin deficiency, cystic fibrosis, and neurological diseases. Dr. Flotte has contributed to the field through various publications addressing the advancements and challenges in gene therapy methodologies and their applications in clinical settings.

Articles (13)

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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FRANCE

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Terence Flotte

Research Interests

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Articles (13)

Gene therapy then and now: A look back at changes in the field over the past 25 years

Limb Perfusion Delivery of a rAAV1 Alpha-1 Antitrypsin Vector in Non-Human Primates Is Safe but Insufficient for Therapy

The Road Less Traveled: Slow but Steady Progress Toward Cystic Fibrosis Gene Therapy by the UK Respiratory Gene Therapy Consortium

Intrathecal gene therapy for neurologic disease in humans

Immunogenicity of Recombinant Adeno-Associated Virus (AAV) Vectors for Gene Transfer

Analyzing clinical observations to better understand and manage immune responses to AAV gene therapies

Gene therapy for alpha-1 antitrypsin deficiency: an update

Future Directions and Resource Needs for National Heart, Lung, and Blood Institute (NHLBI) Gene Therapy Research: A Report of an NHLBI Workshop

Gene-based therapeutics for rare genetic neurodevelopmental psychiatric disorders.

Secretion of functional α1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy

AAV gene therapy for Tay-Sachs disease

Liver-directed SERPINA1 gene therapy attenuates progression of spontaneous and tobacco smoke-induced emphysema in α1-antitrypsin null mice

Gene Therapy for Rare Neurological Disorders

Collaborators (7)

Dan Wang

Allison Keeler-Klunk

Allison Bradbury

Daniel Hebert

Lila Gierasch

Beverly Davidson

Gwladys Gernoux

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